Gene

rbfox1

ID

ZDB-GENE-040927-11

Name

RNA binding fox-1 homolog 1

Symbol

rbfox1 Nomenclature History

Previous Names

a2bp1
zgc:103635 (1)

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to enable mRNA binding activity. Acts upstream of or within heart contraction; hypothalamus development; and regulation of alternative mRNA splicing, via spliceosome. Predicted to be active in cytoplasm and nucleus. Is expressed in digestive system; heart; nervous system; neural keel; and skeletal muscle. Orthologous to human RBFOX1 (RNA binding fox-1 homolog 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UCSC scRNA-seq

Thisse Expression Data

MGC:103635 (9 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 5 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rbfox1 Human Ortholog

No data available

Associated With rbfox1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000504	RNA recognition motif domain
Domain	IPR025670	Fox-1 C-terminal domain
Domain	IPR034237	FOX1, RNA recognition motif
Family	IPR017325	RNA binding protein Fox-1
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	Fox-1 C-terminal domain	FOX1, RNA recognition motif	Nucleotide-binding alpha-beta plait domain superfamily	RNA-binding domain superfamily	RNA binding protein Fox-1	RNA recognition motif domain
UniProtKB:A0A2R8RXA1 InterPro	371
UniProtKB:A0A0R4IV43 InterPro	368
UniProtKB:Q642J5 InterPro	373
UniProtKB:I3ITF6 InterPro	151
UniProtKB:I3IRZ3 InterPro	233
UniProtKB:I3ISD3 InterPro	205
UniProtKB:I3IS31 InterPro	175

Transcripts

Genome Browsers

Type	Name	Length (nt)	Analysis
mRNA	rbfox1-202 (1) Ensembl	3190 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	rbfox1-203 (1) Ensembl	944 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	rbfox1-204 (1) Ensembl	759 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	rbfox1-205 (1) Ensembl	774 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	rbfox1-206 (1) Ensembl	865 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	rbfox1-002 (1) Ensembl	662 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations