ZFIN ID: ZDB-GENE-040912-185
Gene Name: tropomodulin 2
Gene Symbol: tmod2    Nomenclature History

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Previous Name: zgc:86648 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to have tropomyosin binding activity. Predicted to be involved in actin filament organization; muscle contraction; and myofibril assembly. Predicted to localize to striated muscle thin filament. Orthologous to human TMOD2 (tropomodulin 2) and TMOD3 (tropomodulin 3).
Genome Resources: Alliance (1),  Gene:447869 (1),  Ensembl(GRCz11):ENSDARG00000002571 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:6893873]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa17697 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa29074 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tmod2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH tmod2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process pointed-end actin filament capping (more)
    Cellular Component cytoskeleton (more)
    Molecular Function tropomyosin binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA tmod2-201 (1)    Ensembl 1476
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tmod2 No data available
    MARKER RELATIONSHIPS
    tmod2 Contained in: [BAC] CH211-12A1 (1), DKEY-14B24 (1) (order this)
    tmod2 Encodes: [EST] IMAGE:6893873 (1)
    [cDNA] MGC:86648 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001004608 (1) 1488 nt
    Genomic GenBank:BX927313 (1) 189797 nt
    Select Tool
    Polypeptide UniProtKB:F1QJZ6 (1) 344 aa
    Sequence Information (all 14)
    ORTHOLOGY for tmod2 ( Chr: 18 )
    CITATIONS (22)