ZFIN ID: ZDB-GENE-040910-2
Gene Name: synaptonemal complex protein 3
Gene Symbol: sycp3    Nomenclature History

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Previous Names: sycp3l, zgc:136951

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Predicted to be involved in meiotic cell cycle and spermatid development. Predicted to localize to synaptonemal complex. Is expressed in germ line cell and reproductive system. Human ortholog(s) of this gene implicated in spermatogenic failure 4. Orthologous to several human genes including SYCP3 (synaptonemal complex protein 3).
Genome Resources: Alliance (1),  Gene:678602 (1),  Ensembl(GRCz11):ENSDARG00000013438 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa32527 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44282 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH sycp3 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    spermatogenic failure 4 Alliance Pregnancy loss, recurrent, 4 270960
    Spermatogenic failure 4 270960
    DISEASE ASSOCIATED WITH sycp3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process meiotic cell cycle (more)
    Cellular Component synaptonemal complex (more)
    Molecular Function molecular_function (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA sycp3-201 (1)    Ensembl 1220
    sycp3-202 (1)    Ensembl 574
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-sycp3 polyclonal Rabbit IHC, WB 5
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM sycp3 No data available
    MARKER RELATIONSHIPS
    sycp3 Contained in: [BAC] CH211-59O9 (1)
    sycp3 Encodes: [cDNA] MGC:136951 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001040350 (1) 1237 nt
    Genomic GenBank:CR385081 (1) 182806 nt
    Select Tool
    Polypeptide UniProtKB:Q1RLP7 (1) 240 aa
    Sequence Information (all 10)
    ORTHOLOGY for sycp3 ( Chr: 25 )
    CITATIONS (60)