Gene

her11

ID
ZDB-GENE-040824-4
Name
hairy-related 11
Symbol
her11 Nomenclature History
Previous Names
  • him (1)
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Exhibits protein heterodimerization activity. Involved in midbrain-hindbrain boundary development and negative regulation of neurogenesis. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in spondylocostal dysostosis. Is expressed in several structures, including heart; liver; margin; midbrain hindbrain boundary; and midbrain hindbrain boundary neural plate. Orthologous to human HES7 (hes family bHLH transcription factor 7).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With her11 Human Ortholog
No data available
Associated With her11 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Family IPR032644 Transcription factor HES-7
Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Helix-loop-helix DNA-binding domain superfamily Myc-type, basic helix-loop-helix (bHLH) domain Transcription factor HES-7
UniProtKB:Q6W4T8 274
UniProtKB:Q66T09 264
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations