ZFIN ID: ZDB-GENE-040808-45
Gene Name: ALG6 alpha-1,3-glucosyltransferase
Gene Symbol: alg6    Nomenclature History

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Previous Name: zgc:100813 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity. Predicted to be involved in oligosaccharide-lipid intermediate biosynthetic process and protein N-linked glycosylation. Predicted to localize to the endoplasmic reticulum and endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ic. Orthologous to human ALG6 (ALG6 alpha-1,3-glucosyltransferase).
Genome Resources: Alliance (1),  Gene:445327 (1),  Ensembl(GRCz11):ENSDARG00000017617 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:6901735]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la015888Tg Transgenic Insertion Unknown Unknown DNA
PHENOTYPE No data available
DISEASE ASSOCIATED WITH alg6 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
congenital disorder of glycosylation Ic Alliance Congenital disorder of glycosylation, type Ic 603147
DISEASE ASSOCIATED WITH alg6 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process protein N-linked glycosylation (more)
Cellular Component endoplasmic reticulum (more)
Molecular Function glucosyltransferase activity (more)
GO Terms (all 12)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Family IPR004856 Glycosyl transferase, ALG6/ALG8
Family IPR039488 Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA alg6-201 (1)    Ensembl 2011
alg6-202 (1)    Ensembl 1944
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM alg6 No data available
MARKER RELATIONSHIPS
alg6 Contained in: [BAC] DKEY-148H10 (1) (order this)
alg6 Encodes: [EST] IMAGE:6901735 (1)
[cDNA] MGC:100813 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001003784 (1) 2080 bp
Genomic GenBank:BX664614 (1) 184225 bp
Select Tool
Polypeptide UniProtKB:I3IT66 (1) 506 aa
Sequence Information (all 15)
ORTHOLOGY for alg6 ( Chr: 6 )
CITATIONS (27)