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General Information
ZIRC
ZFIN ID: ZDB-GENE-040808-32
Gene Name: cholinergic receptor, nicotinic, epsilon
Gene Symbol: chrne
Sequence Ontology ID : SO:0001217

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Previous Names: AChR epsilon (1), im:7154697, zgc:101010

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Contributes to acetylcholine receptor activity. Involved in cholinergic synaptic transmission. Localizes to the acetylcholine-gated channel complex. Human ortholog(s) of this gene implicated in  ...
GENE EXPRESSION
All Expression Data: 7 figures from 3 publications
Directly Submitted Expression Data: 5 figures (9 images) from Thisse et al., 2004 [IMAGE:7154697]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa15968 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18813 Point Mutation Unknown Premature Stop ENU
    Targeting reagents:
    DISEASE ASSOCIATED WITH chrne HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    congenital myasthenic syndrome 4A Myasthenic syndrome, congenital, 4A, slow-channel 605809
    congenital myasthenic syndrome 4B Myasthenic syndrome, congenital, 4B, fast-channel 616324
    congenital myasthenic syndrome 4C Myasthenic syndrome, congenital, 4C, associated with acetylcholine receptor deficiency 608931
    DISEASE ASSOCIATED WITH chrne VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process synaptic transmission, cholinergic (more)
    Cellular Component acetylcholine-gated channel complex (more)
    Molecular Function CONTRIBUTES_TO   acetylcholine receptor activity (more)
    GO Terms (all 24)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA chrne-201 (1) 2557
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM chrne No data available
    MARKER RELATIONSHIPS
    chrne Contained in: [BAC] CH211-147A23 (1) (order this), DKEY-89J23 (1) (order this)
    chrne Encodes: [EST] IMAGE:7154697 (1) (order this)
    [cDNA] MGC:101010 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001003772 (1) 1475 bp
    Genomic GenBank:BX324194 (1) 187691 bp
    Select Tool
    Polypeptide UniProtKB:A2BG85 (1) 517 aa
    Sequence Clusters UniGene:85037 (1)
    Sequence Information (all 16)
    ORTHOLOGY for chrne ( Chr: 5 )
    CITATIONS (26)