ZFIN ID: ZDB-GENE-040806-2
Gene Name: luteinizing hormone, beta polypeptide
Gene Symbol: lhb
Sequence Ontology ID : SO:0000704

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Previous Names: LHB, Gth II, gthII, LH Beta, zgc:92312

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(Including Attributions)
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 18 figures from 11 publications
Wild-type Stages, Structures: Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) to Adult (90d-730d, breeding adult)
  adenohypophysis, brain, female organism proximal pars anterior, gill (all 13) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa30366 Point Mutation Unknown Premature Stop ENU
sa44382 Point Mutation Unknown Premature Stop ENU
umo2 Small Deletion Exon 2 Unknown TALEN
zf592 Indel Exon 2 Frameshift TALEN
zf594 Indel Exon 2 Unknown TALEN
Targeting reagents: MO1-lhb (1), MO2-lhb (1), MO3-lhb (1), TALEN1-lhb (1), TALEN2-lhb (1)
PHENOTYPE
Data: 10 figures from 6 publications
Observed in: female organism, oocyte maturation, oocyte stage IV, ovarian follicle stage III (all 10) expand
DISEASE ASSOCIATED WITH lhb HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
hypogonadotropic hypogonadism 23 with or without anosmia Hypogonadotropic hypogonadism 23 with or without anosmia 228300
GENE ONTOLOGY
Ontology GO Term
Biological Process female gonad development (more)
Cellular Component extracellular region (more)
Molecular Function hormone activity (more)
GO Terms (all 12)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001545 (1)
  • InterPro:IPR006208 (1)
  • InterPro:IPR018245 (1)
  • InterPro:IPR029034 (1)
  • PROSITE:PS00261 (1)
  • PROSITE:PS00689 (1)
  • Pfam:PF00007 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA lhb-001 (1) 1378
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Ab1-lhb (1)
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM lhb No data available
    MARKER RELATIONSHIPS
    lhbContained in: [Fosmid] CH1073-470L8 (1) (order this)
    lhbEncodes: [cDNA] MGC:92312 (1) (order this), MGC:193585 (1) (order this), MGC:193602 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_205622 (1) 1371bp
    Genomic GenBank:CU928134 (1) 33143bp
    Select Tool
    Polypeptide UniProtKB:Q5UK78 (1) 140aa
    Sequence Clusters UniGene:90074 (1)
    Sequence Information (all 36)
    OTHER lhb GENE PAGES
  • Alliance (1)
  • Gene:402917 (1)
  • VEGA:OTTDARG00000035312 (1)
  • Ensembl(GRCz10):ENSDARG00000099363 (1)
  • ORTHOLOGY for lhb (Chr: 13)
    CITATIONS (88)