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ZIRC
ZFIN ID: ZDB-GENE-040806-1
Gene Name: follicle stimulating hormone subunit beta
Gene Symbol: fshb    Nomenclature History

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Previous Names: FSHB, FSH Beta, Gth I, gthI

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Exhibits hormone activity. Involved in ovarian follicle development; sex determination; and spermatogenesis. Predicted to localize to the cytoplasm and extracellular space. Human ortholog(s) of this gene implicated in amenorrhea and hypogonadotropic hypogonadism 24 without anosmia. Is expressed in several structures, including brain; endocrine system; female organism; kidney; and male organism. Orthologous to human FSHB (follicle stimulating hormone subunit beta).
Genome Resources: Alliance (1),  Gene:402919 (1),  Ensembl(GRCz11):ENSDARG00000010841 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb351 Indel Exon 1 Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • umo1 Small Deletion Exon 2 Frameshift TALEN
    zf686 Indel Exon 2 Frameshift, Premature Stop TALEN
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-fshb 1
    MO1-fshb N/A 1
    TALEN1-fshb 1
    TALEN2-fshb 1
    DISEASE ASSOCIATED WITH fshb HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    hypogonadotropic hypogonadism 24 without anosmia Alliance Hypogonadotropic hypogonadism 24 without anosmia 229070
    DISEASE ASSOCIATED WITH fshb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process female gonad development (more)
    Cellular Component extracellular region (more)
    Molecular Function hormone activity (more)
    GO Terms (all 10)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA fshb-202 (1)    Ensembl 1013
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-fshb Rabbit WB 5
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM fshb No data available
    MARKER RELATIONSHIPS
    fshb Contained in: [BAC] CH73-314G15 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_205624 (1) 1038 bp
    Genomic GenBank:CT030129 (1) 102729 bp
    Select Tool
    Polypeptide UniProtKB:Q6TCF7 (1) 130 aa
    Sequence Clusters UniGene:90853 (1)
    Sequence Information (all 14)
    ORTHOLOGY for fshb ( Chr: 7 )
    CITATIONS (121)