Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-040801-39
Gene Name: desumoylating isopeptidase 2
Gene Symbol: desi2
Previous Names: desi1, cb238 (1), fam152a, fi12d12, pnas4 (1), pppde1, sb:cb238 (1), wu:fi12d12, zgc:100860 (1)
Location: Chr: 13   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 7 figures from 2 publications
Directly Submitted Expression Data: 6 figures (11 images) from Thisse et al., 2001 [cb238]
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Hatching:Long-pec (48.0h-60.0h)
  cranial ganglion, diencephalon, forebrain, head (all 17) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Knockdown reagents: MO1-desi2 (1)
PHENOTYPE
Data: 2 figures from Yao et al., 2008
Observed in: axis, convergent extension involved in gastrulation, gastrulation, neural plate (all 8) expand
GENE ONTOLOGY
Ontology GO Term
Biological Process convergent extension involved in gastrulation (more)
Cellular Component cytoplasm (more)
Molecular Function cysteine-type peptidase activity (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR008580 (1)
  • Pfam:PF05903 (1)
  • EC:3.4.-.- (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA desi2-001 (1) 1764
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM desi2 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    desi2 Contained in: [BAC] CH211-132E22 (1) (order this), DKEY-159A12 (1), DKEY-195J22 (1)
    desi2 Encodes: [EST] cb238 (order this), fi12d12
    [cDNA] MGC:100860 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001003532 (1) 1795 bp
    Genomic GenBank:CR556710 (1) 97211 bp
    Select Tool
    Polypeptide UniProtKB:Q6DC39 (1) 196 aa
    Sequence Clusters UniGene:6944 (1)
    Sequence Information (all 16)
    OTHER desi2 GENE PAGES
  • Gene:445138 (1)
  • VEGA:OTTDARG00000013542 (1)
  • Ensembl(Zv9):ENSDARG00000004460 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish desi2 13  
    Human DESI2 1 (1q44)
  • OMIM:614638
  • Gene:51029
  • Mouse Desi2 1 ( 82.93 cM)
  • MGI:1926075
  • Gene:78825
  • Orthology Details
    CITATIONS (16)