ZFIN ID: ZDB-GENE-040801-39
Gene Name: desumoylating isopeptidase 2
Gene Symbol: desi2
Previous Names: desi1, cb238 (1), fam152a, fi12d12, pnas4 (1), pppde1, sb:cb238 (1), wu:fi12d12, zgc:100860 (1)
Location: Chr: 13 Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 7 figures from 2 publications
Directly Submitted Expression Data: 6 figures (11 images) from Thisse et al., 2001 [cb238]
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Hatching:Long-pec (48.0h-60.0h)
  cranial ganglion, diencephalon, forebrain, head (all 17) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents: MO1-desi2 (1)
PHENOTYPE
Data: 2 figures from Yao et al., 2008
Observed in: axis, convergent extension involved in gastrulation, gastrulation, neural plate (all 8) expand
DISEASE ASSOCIATED WITH desi2 HUMAN ORTHOLOGNo data available
GENE ONTOLOGY
Ontology GO Term
Biological Process convergent extension involved in gastrulation (more)
Cellular Component cytoplasm (more)
Molecular Function cysteine-type peptidase activity (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR008580 (1)
  • Pfam:PF05903 (1)
  • EC:3.4.-.- (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA desi2-001 (1) 1764
    desi2-002 (1) 523
    GENE PRODUCT DESCRIPTION
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM desi2 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    desi2Contained in: [BAC] CH211-132E22 (1) (order this), DKEY-159A12 (1) (order this), DKEY-195J22 (1) (order this)
    desi2Encodes: [EST] cb238 (order this), fi12d12
    [cDNA] MGC:100860 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001003532 (1) 1795bp
    Genomic GenBank:CR556710 (1) 97211bp
    Select Tool
    Polypeptide UniProtKB:Q6DC39 (1) 196aa
    Sequence Clusters UniGene:6944 (1)
    Sequence Information (all 16)
    OTHER desi2 GENE PAGES
  • Gene:445138 (1)
  • VEGA:OTTDARG00000013542 (1)
  • VEGA:OTTDARG00000042078 (1)
  • Ensembl(GRCz10):ENSDARG00000004460 (1)
  • ORTHOLOGY for desi2 (Chr: 13)
    Species Symbol Chromosome Accession # Evidence
    Human DESI2 1
  • Gene:51029
  • OMIM:614638
  • HGNC:24264
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Mouse Desi2 1
  • MGI:1926075
  • Gene:78825
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (16)