ZFIN ID: ZDB-GENE-040801-242
Gene Name: lipase, member Ia
Gene Symbol: lipia    Nomenclature History

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Previous Names: fb08f08, wu:fb08f08, zgc:91985

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to have phospholipase activity. Predicted to be involved in lipid catabolic process. Predicted to localize to the extracellular space. Human ortholog(s) of this gene implicated in hypotrichosis 7. Is expressed in notochord. Orthologous to several human genes including LIPH (lipase H).
Genome Resources: Alliance (1),  Gene:445105 (1),  Ensembl(GRCz11):ENSDARG00000007108 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 2 figures (2 images) from Thisse et al., 2004 [IMAGE:7138600]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Segmentation:14-19 somites (16.0h-19.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa14145 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39339 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43686 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44973 Point Mutation Unknown Unknown ENU
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH lipia HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH lipia VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process lipid catabolic process (more)
    Cellular Component extracellular region (more)
    Molecular Function carboxylic ester hydrolase activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Family IPR000734 Triacylglycerol lipase family
    Domain IPR013818 Lipase/vitellogenin
    Family IPR016272 Lipase, LIPH-type
    Homologous_superfamily IPR029058 Alpha/Beta hydrolase fold
    Domain IPR033906 Lipase, N-terminal
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA lipia-201 (1)    Ensembl 1777
    lipia-202 (1)    Ensembl 766
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lipia No data available
    MARKER RELATIONSHIPS
    lipia Contained in: [BAC] DKEY-71D15 (1) (order this)
    lipia Encodes: [EST] fb08f08, IMAGE:7138600 (1)
    [cDNA] MGC:91985 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001003499 (1) 1680 bp
    Genomic GenBank:CR388019 (1) 68996 bp
    Select Tool
    Polypeptide UniProtKB:Q6DBU8 (1) 454 aa
    Sequence Information (all 14)
    ORTHOLOGY for lipia ( Chr: 21 )
    CITATIONS (22)