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Gene

ctps1b

ID
ZDB-GENE-040801-160
Name
CTP synthase 1b
Symbol
ctps1b Nomenclature History
Previous Names
  • ctpsb
  • zgc:100914
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to enable CTP synthase activity and identical protein binding activity. Acts upstream of or within notochord development. Predicted to be active in cytoophidium and cytoplasm. Is expressed in blood cell and vascular endothelium. Human ortholog(s) of this gene implicated in immunodeficiency 24. Orthologous to several human genes including CTPS1 (CTP synthase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Cannon et al., 2013
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Dzaki et al., 2018
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ctps1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
immunodeficiency 24 Alliance Immunodeficiency 24 615897
Associated With ctps1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017456 CTP synthase, N-terminal
Domain IPR017926 Glutamine amidotransferase
Domain IPR033828 CTP synthase GATase domain
Family IPR004468 CTP synthase
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR029062 Class I glutamine amidotransferase-like
Domain Details Per Protein
Protein Length Class I glutamine amidotransferase-like CTP synthase CTP synthase GATase domain CTP synthase, N-terminal Glutamine amidotransferase P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A0A2R8QCI7 610
UniProtKB:A9JT21 589
UniProtKB:Q6DBZ3 445
UniProtKB:A0A2R8Q6Q1 567
UniProtKB:B7ZVK1 589
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations