ZFIN ID: ZDB-GENE-040801-132
Gene Name: splicing regulatory glutamine/lysine-rich protein 1
Gene Symbol: srek1    Nomenclature History

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Previous Name: zgc:100974 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have RNA binding activity. Predicted to be involved in regulation of alternative mRNA splicing, via spliceosome. Predicted to localize to nucleoplasm. Orthologous to human SREK1 (splicing regulatory glutamic acid and lysine rich protein 1).
Genome Resources: Alliance (1),  Gene:445219 (1),  Ensembl(GRCz11):ENSDARG00000009764 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7148031]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la029126Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa6064 Point Mutation Unknown Splice Site ENU
    sa13077 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20535 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40563 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH srek1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH srek1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of alternative mRNA splicing, via spliceosome (more)
    Cellular Component nucleoplasm (more)
    Molecular Function nucleic acid binding (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA srek1-201 (1)    Ensembl 1879
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM srek1 No data available
    MARKER RELATIONSHIPS
    srek1 Contained in: [BAC] CH211-10H13 (1)
    srek1 Encodes: [EST] IMAGE:7148031 (1)
    [cDNA] MGC:100974 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001003613 (1) 1990 nt
    Genomic GenBank:BX950207 (1) 129862 nt
    Select Tool
    Polypeptide UniProtKB:A2BIN4 (1) 515 aa
    Sequence Information (all 26)
    ORTHOLOGY for srek1 ( Chr: 5 )
    CITATIONS (23)