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ZIRC
ZFIN ID: ZDB-GENE-040727-4
Gene Name: mediator complex subunit 19b
Gene Symbol: med19b    Nomenclature History

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Previous Names: med19 (1), lcmr1l (1), zgc:110121

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have transcription factor binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to localize to the mediator complex. Orthologous to human MED19 (mediator complex subunit 19).
Genome Resources: Alliance (1),  Gene:445021 (1),  Ensembl(GRCz11):ENSDARG00000009472 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:110121]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi1518Tg Transgenic Insertion Exon 1 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • hi1642Tg Transgenic Insertion Intron 1 Unknown DNA
    sa14484 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zko841a Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • zko841b Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-med19b 1
    PHENOTYPE
    Data: 3 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH med19b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH med19b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of transcription by RNA polymerase II (more)
    Cellular Component mediator complex (more)
    Molecular Function transcription coregulator activity (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR019403 (1)
  • Pfam:PF10278 (1)
  • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA med19b-202 (1)    Ensembl 1177
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM med19b No data available
    MARKER RELATIONSHIPS
    med19b Contained in: [BAC] DKEY-28B4 (1) (order this)
    med19b Encodes: [cDNA] MGC:110121 (1) (order this), MGC:192263 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001003416 (1) 1165 bp
    Genomic GenBank:BX511158 (1) 198706 bp
    Select Tool
    Polypeptide UniProtKB:B8A5B3 (1) 259 aa
    Sequence Clusters UniGene:86691 (1)
    Sequence Information (all 18)
    ORTHOLOGY for med19b ( Chr: 1 )
    CITATIONS (28)