ZFIN ID: ZDB-GENE-040724-230
Gene Name: glyoxylate reductase/hydroxypyruvate reductase a
Gene Symbol: grhpra
Sequence Ontology ID : SO:0000704

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Previous Names: grhpr, si:ch211-240l14.3, zgc:109900

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(Including Attributions)
Location: Chr: 14 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have glyoxylate reductase (NADP) activity, hydroxypyruvate reductase activity, and protein homodimerization activity; predicted to be involved in oxidation-reduction process; predicted  ...
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7152758]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa22536 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH grhpra HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    primary hyperoxaluria Hyperoxaluria, primary, type II 260000
    DISEASE ASSOCIATED WITH grhpra VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process oxidation-reduction process (more)
    Cellular Component cytosol (more)
    Molecular Function NAD binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR006139 (1)
  • InterPro:IPR006140 (1)
  • InterPro:IPR029753 (1)
  • InterPro:IPR036291 (1)
  • PROSITE:PS00671 (1)
  • Pfam:PF00389 (1)
  • Pfam:PF02826 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA grhpra-001 (1) 1413
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM grhpra No data available
    MARKER RELATIONSHIPS
    grhpraContained in: [BAC] CH211-240L14 (order this), DKEY-109L4 (1) (order this)
    grhpraEncodes: [EST] IMAGE:7152758 (1) (order this)
    [cDNA] MGC:109900 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001020525 (1) 1380bp
    Genomic GenBank:CT573279 (1) 264426bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q504F9 (1) 327aa
    Sequence Clusters UniGene:40458 (1)
    Sequence Information (all 13)
    OTHER grhpra GENE PAGES
  • Alliance (1)
  • Gene:497183 (1)
  • VEGA:OTTDARG00000028283 (1)
  • Ensembl(GRCz11):ENSDARG00000068264 (2)
  • ORTHOLOGY for grhpra (Chr: 14)
    CITATIONS (18)