ZFIN ID: ZDB-GENE-040724-208
Gene Name: transforming growth factor, alpha
Gene Symbol: tgfa
Sequence Ontology ID : SO:0000704

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Previous Name: si:ch211-10e8.7

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(Including Attributions)
Location: Chr: 6 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have epidermal growth factor receptor binding activity and growth factor activity; predicted to be involved in epidermal growth factor receptor signaling pathway and positive regulation  ...
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ct816 Small Deletion Unknown Unknown TALEN
Targeting reagents:
PHENOTYPE No data available
DISEASE ASSOCIATED WITH tgfa HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH tgfa VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process activation of MAPK activity (more)
Cellular Component integral component of membrane (more)
Molecular Function epidermal growth factor receptor binding (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000742 (1)
  • InterPro:IPR013032 (1)
  • InterPro:IPR015497 (1)
  • PROSITE:PS00022 (1)
  • PROSITE:PS01186 (1)
  • PROSITE:PS50026 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tgfa-202 (1) 3007
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tgfa No data available
    MARKER RELATIONSHIPS
    tgfaContained in: [BAC] CH211-10E8 (order this), CH211-13J1 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001144052 (1) 576bp
    Genomic GenBank:CR293534 (1) 109426bp
    Select Tool
    Polypeptide UniProtKB:Q7T011 (1) 191aa
    Sequence Clusters UniGene:154690 (1)
    Sequence Information (all 19)
    OTHER tgfa GENE PAGES
  • Alliance (1)
  • Gene:100034402 (1)
  • VEGA:OTTDARG00000002188 (1)
  • Ensembl(GRCz11):ENSDARG00000053939 (1)
  • ORTHOLOGY for tgfa (Chr: 6)
    CITATIONS (22)