Gene

tgfa

ID
ZDB-GENE-040724-208
Name
transforming growth factor, alpha
Symbol
tgfa Nomenclature History
Previous Names
  • si:ch211-10e8.7
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have epidermal growth factor receptor binding activity and growth factor activity. Predicted to be involved in epidermal growth factor receptor signaling pathway and positive regulation of cell population proliferation. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in gastroenteritis and pancreatic cancer. Is expressed in midbrain; retina; and third ventricle. Orthologous to human TGFA (transforming growth factor alpha).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tgfa Human Ortholog
No data available
Associated With tgfa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000742 EGF-like domain
Family IPR015497 Epidermal growth factor receptor ligand
Domain Details Per Protein
Protein Length EGF-like domain Epidermal growth factor receptor ligand
UniProtKB:I3ISP4 188
UniProtKB:Q7T011 191
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations