ZFIN ID: ZDB-GENE-040724-181
Gene Name: arginase 1
Gene Symbol: arg1    Nomenclature History

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Previous Name: si:ch211-146f4.3 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to have arginase activity and manganese ion binding activity. Predicted to be involved in arginine catabolic process to ornithine. Predicted to localize to cytosol. Is expressed in digestive system; eye; and reproductive system. Human ortholog(s) of this gene implicated in asthma; hepatocellular carcinoma; and hyperargininemia. Orthologous to human ARG1 (arginase 1).
Genome Resources: Alliance (1),  Gene:570368 (1),  Ensembl(GRCz11):ENSDARG00000057429 (1)
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Wild-type Stages, Structures: Hatching:Long-pec (48.0h-60.0h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH arg1 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hyperargininemia Alliance Argininemia 207800
DISEASE ASSOCIATED WITH arg1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process arginine metabolic process (more)
Cellular Component cytoplasm (more)
Molecular Function arginase activity (more)
GO Terms (all 10)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA arg1-201 (1)    Ensembl 1041
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM arg1 No data available
MARKER RELATIONSHIPS
arg1 Contained in: [BAC] CH211-146F4
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001045197 (1)
Genomic GenBank:AL732629 (1) 164474 nt
Select Tool
Polypeptide UniProtKB:E7F8R4 (1) 341 aa
Sequence Information (all 8)
ORTHOLOGY for arg1 ( Chr: 12 )
CITATIONS (22)