ZFIN ID: ZDB-GENE-040718-44
Gene Name: R-spondin 1
Gene Symbol: rspo1
Sequence Ontology ID : SO:0000704

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Previous Names: cb1071 (1), fj81e05, wu:fj81e05, zgc:92153 (1)

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(Including Attributions)
Location: Chr: 16 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have frizzled binding activity; involved in angiogenesis and vascular endothelial growth factor receptor signaling pathway; localizes to the Golgi apparatus and cytosol; orthologous to  ...
GENE EXPRESSION
All Expression Data: 12 figures from 7 publications
Directly Submitted Expression Data: 3 figures (6 images) from Thisse et al., 2001 [cb1071]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
PHENOTYPE
Data: 15 figures from 2 publications
Observed in:
DISEASE ASSOCIATED WITH rspo1 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
Palmoplantar hyperkeratosis and true hermaphroditism 610644
Palmoplantar hyperkeratosis with squamous cell carcinoma of skin and sex reversal 610644
DISEASE ASSOCIATED WITH rspo1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process angiogenesis (more)
Cellular Component cytosol (more)
Molecular Function heparin binding (more)
GO Terms (all 11)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000884 (1)
  • InterPro:IPR006212 (1)
  • InterPro:IPR009030 (1)
  • InterPro:IPR036383 (1)
  • PROSITE:PS50092 (1)
  • Pfam:PF15913 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA rspo1-201 (1) 2598
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM rspo1 No data available
    MARKER RELATIONSHIPS
    rspo1Contained in: [BAC] CH211-232M19 (2) (order this)
    rspo1Encodes: [EST] cb1071 (order this), fj81e05
    [cDNA] MGC:92153 (1) (order this), MGC:173850 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001002352 (1) 2517bp
    Genomic GenBank:BX530064 (1) 153572bp
    Select Tool
    Polypeptide UniProtKB:A8KBP5 (1) 261aa
    Sequence Clusters UniGene:161789 (1)
    Sequence Information (all 22)
    OTHER rspo1 GENE PAGES
  • Alliance (1)
  • Gene:436625 (1)
  • VEGA:OTTDARG00000022325 (1)
  • ORTHOLOGY for rspo1 (Chr: 16)
    CITATIONS (43)