ZFIN ID: ZDB-GENE-040718-44
Gene Name: R-spondin 1
Gene Symbol: rspo1
Sequence Ontology ID : SO:0000704

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Previous Names: cb1071 (1), fj81e05, wu:fj81e05, zgc:92153 (1)

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(Including Attributions)
Location: Chr: 16 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 10 figures from 6 publications
Directly Submitted Expression Data: 3 figures (6 images) from Thisse et al., 2001 [cb1071]
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Adult (90d-730d, breeding adult)
  brain, diencephalon, eye, gonad (all 24) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la012937Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la027735Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12606 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa16782 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16889 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36198 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa42772 Point Mutation Unknown Premature Stop ENU
    y135 Point Mutation Unknown Missense ENU
    Targeting reagents: MO1-rspo1 (1), MO2-rspo1 (1), MO3-rspo1 (1), MO4-rspo1 (1)
    PHENOTYPE
    Data: 5 figures from Gore et al., 2011
    Observed in: angiogenesis, anterior mesencephalic central artery, cerebellar central artery, extension (all 10) expand
    DISEASE ASSOCIATED WITH rspo1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Palmoplantar hyperkeratosis and true hermaphroditism 610644
    Palmoplantar hyperkeratosis with squamous cell carcinoma of skin and sex reversal 610644
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process angiogenesis (more)
    Cellular Component Golgi apparatus (more)
    Molecular Function heparin binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000884
  • InterPro:IPR006212
  • InterPro:IPR009030
  • PROSITE:PS50092
  • Pfam:PF15913
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA rspo1-001 (1) 2598
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM rspo1 No data available
    MARKER RELATIONSHIPS
    rspo1Contained in: [BAC] CH211-232M19 (2) (order this)
    rspo1Encodes: [EST] cb1071 (order this), fj81e05
    [cDNA] MGC:92153 (1) (order this), MGC:173850 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001002352 (1) 2517bp
    Genomic GenBank:BX530064 (1) 153572bp
    Select Tool
    Polypeptide UniProtKB:A8KBP5 261aa
    Sequence Clusters UniGene:161789 (1)
    Sequence Information (all 22)
    OTHER rspo1 GENE PAGES
  • Gene:436625 (1)
  • VEGA:OTTDARG00000022325 (1)
  • Ensembl(GRCz10):ENSDARG00000104340 (1)
  • ORTHOLOGY for rspo1 (Chr: 16)
    CITATIONS (33)