Gene
s100b
- ID
- ZDB-GENE-040718-290
- Name
- S100 calcium binding protein, beta (neural)
- Symbol
- s100b Nomenclature History
- Previous Names
-
- si:dkey-110p14.2
- wu:fq18b10
- zgc:92776
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to enable several functions, including RAGE receptor binding activity; S100 protein binding activity; and calcium-dependent protein binding activity. Predicted to be involved in positive regulation of I-kappaB kinase/NF-kappaB signaling and positive regulation of cell population proliferation. Predicted to be active in cytoplasm; extracellular space; and nucleus. Is expressed in several structures, including digestive system; heart; integument; nervous system; and renal system. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; aspergillosis; and schizophrenia. Orthologous to human S100B (S100 calcium binding protein B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
-
- GEO (1) Expression Atlas (1) UCSC scRNA-seq (1)
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | EF-hand domain | EF-hand domain pair | Protein S100-A4 | Protein S100-B | S100/CaBP-9k-type, calcium binding, subdomain | S100/Calbindin-D9k, conserved site |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6DGT8
|
95 |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-s100 | polyclonal | Rabbit |
|
Dako North America, Inc.
|
73 |
Plasmids
No data available