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General Information
ZIRC
ZFIN ID: ZDB-GENE-040718-219
Gene Name: dual specificity phosphatase 22a
Gene Symbol: dusp22a    Nomenclature History

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Previous Names: dusp22, wu:fa11e09, zgc:92816

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to have protein tyrosine phosphatase activity and protein tyrosine/serine/threonine phosphatase activity. Predicted to be involved in positive regulation of JNK cascade; regulation of cell population proliferation; and transforming growth factor beta receptor signaling pathway. Predicted to localize to the cytosol. Orthologous to human DUSP22 (dual specificity phosphatase 22).
Genome Resources: Alliance (1),  Gene:436787 (1),  Ensembl(GRCz11):ENSDARG00000056396 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7146559]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa32212 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH dusp22a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dusp22a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process dephosphorylation (more)
    Cellular Component cytoplasm (more)
    Molecular Function hydrolase activity (more)
    GO Terms (all 13)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dusp22a-201 (1)    Ensembl 1308
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dusp22a No data available
    MARKER RELATIONSHIPS
    dusp22a Contained in: [BAC] DKEY-265O13 (1) (order this), DKEYP-77B5 (1)
    dusp22a Encodes: [EST] fa11e09, IMAGE:7146559 (1) (order this)
    [cDNA] MGC:92816 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001002514 (1) 1321 bp
    Genomic GenBank:BX548023 (1) 151449 bp
    Select Tool
    Polypeptide UniProtKB:Q1LWL2 (1) 208 aa
    Sequence Clusters UniGene:75237 (1)
    Sequence Information (all 13)
    ORTHOLOGY for dusp22a ( Chr: 18 )
    CITATIONS (22)