ZFIN ID: ZDB-GENE-040718-186
Gene Name: SRY-box transcription factor 1a
Gene Symbol: sox1a    Nomenclature History

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Previous Names: fi38c08, fj38h03, wu:fi38c08 (1), wu:fj38h03 (1), zgc:92865 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Contributes to DNA-binding transcription factor activity. Involved in positive regulation of DNA-binding transcription factor activity. Predicted to localize to the nuclear transcription factor complex. Is expressed in several structures, including forebrain neural keel; lens placode; nervous system; neural plate; and solid lens vesicle. Orthologous to human SOX1 (SRY-box transcription factor 1).
Genome Resources: Alliance (1),  Gene:436756 (1),  Ensembl(GRCz11):ENSDARG00000069866 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ka701 Small Deletion Unknown Unknown CRISPR
ka705Tg Transgenic Insertion Unknown Unknown DNA_AND_CRISPR
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-sox1a 1
MO1-sox1a,sox1b N/A 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH sox1a HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH sox1a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process positive regulation of DNA-binding transcription factor activity (more)
Cellular Component transcription factor complex (more)
Molecular Function CONTRIBUTES_TO   DNA-binding transcription factor activity (more)
GO Terms (all 12)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR009071 High mobility group box domain
Family IPR022097 Transcription factor SOX
Family IPR031268 Transcription factor SOX-1
Homologous_superfamily IPR036910 High mobility group box domain superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA sox1a-201 (1)    Ensembl 1929
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM sox1a No data available
MARKER RELATIONSHIPS
sox1a Contained in: [BAC] DKEY-58D5 (1) (order this)
sox1a Encodes: [EST] fi38c08, fj38h03
[cDNA] MGC:92865 (1), MGC:113892 (1), MGC:191313 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001002483 (1) 1946 bp
Genomic GenBank:CR392332 (1) 128550 bp
Select Tool
Polypeptide UniProtKB:B2GNY1 (1) 336 aa
Sequence Information (all 23)
ORTHOLOGY for sox1a ( Chr: 9 )
CITATIONS (41)