ZFIN ID: ZDB-GENE-040718-108
Gene Name: OTU deubiquitinase, ubiquitin aldehyde binding 1a
Gene Symbol: otub1a    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: otub1l, fb17f04 (1), wu:fb17f04 (1), zgc:92685

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to have NEDD8-specific protease activity; thiol-dependent ubiquitin-specific protease activity; and ubiquitin binding activity. Predicted to be involved in negative regulation of double-strand break repair; negative regulation of histone H2A K63-linked ubiquitination; and protein K48-linked deubiquitination. Predicted to localize to nucleus. Orthologous to human OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1).
Genome Resources: Alliance (1),  Gene:436684 (1),  Ensembl(GRCz11):ENSDARG00000055536 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:92685]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la014051Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa5960 Point Mutation Unknown Premature Stop ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-otub1a N/A 2
    DISEASE ASSOCIATED WITH otub1a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH otub1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein deubiquitination (more)
    Cellular Component nucleus (more)
    Molecular Function cysteine-type peptidase activity (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA otub1a-201 (1)    Ensembl 1169
    otub1a-204 (1)    Ensembl 792
    ncRNA otub1a-002 (1)    Ensembl 532
    otub1a-003 (1)    Ensembl 566
    otub1a-005 (1)    Ensembl 517
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM otub1a No data available
    MARKER RELATIONSHIPS
    otub1a Contained in: [BAC] DKEY-270M17 (1) (order this)
    otub1a Encodes: [EST] fb17f04, IMAGE:7144196 (1)
    [cDNA] MGC:92685 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001002411 (1) 1204 nt
    Genomic GenBank:CR749775 (1) 71543 nt
    Select Tool
    Polypeptide UniProtKB:Q6DH16 (1) 267 aa
    Sequence Information (all 11)
    ORTHOLOGY for otub1a ( Chr: 21 )
    CITATIONS (30)