ZFIN ID: ZDB-GENE-040718-102
Gene Name: arrestin 3a, retinal (X-arrestin)
Gene Symbol: arr3a    Nomenclature History

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Previous Names: arr3l (1), c-arrestin (1), zgc:92697 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to have G protein-coupled receptor binding activity. Involved in visual perception. Is expressed in epiphysis and retina. Human ortholog(s) of this gene implicated in myopia. Orthologous to human ARR3 (arrestin 3).
Genome Resources: Alliance (1),  Gene:436678 (1),  Ensembl(GRCz11):ENSDARG00000056511 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa17404 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34922 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38804 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-arr3a N/A 1
    MO2-arr3a N/A 1
    PHENOTYPE
    Data: Fig. 5 from Renninger et al., 2011
    Observed in:
    DISEASE ASSOCIATED WITH arr3a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Myopia 26, X-linked, female-limited 301010
    DISEASE ASSOCIATED WITH arr3a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process visual perception (more)
    Cellular Component cellular_component (more)
    Molecular Function G protein-coupled receptor binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA arr3a-201 (1)    Ensembl 1724
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-arr3a Rabbit IHC, WB 2
    zpr-1 monoclonal IgG1 , k Mouse IHC Abcam plc
    Zebrafish International Resource Center (ZIRC)  (order this)
    284
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM arr3a No data available
    MARKER RELATIONSHIPS
    arr3a Contained in: [BAC] CH211-263P13 (1)
    arr3a Encodes: [cDNA] MGC:92697 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001002405 (1) 1729 nt
    Genomic GenBank:CR545465 (1) 169902 nt
    Select Tool
    Polypeptide UniProtKB:Q6DH07 (1) 357 aa
    Sequence Information (all 12)
    ORTHOLOGY for arr3a ( Chr: 10 )
    CITATIONS (43)