Gene

irx6a

ID
ZDB-GENE-040712-5
Name
iroquois homeobox 6a
Symbol
irx6a Nomenclature History
Previous Names
  • ziro6a (1)
  • zgc:109993
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific; and sequence-specific DNA binding activity. Predicted to be involved in cell development; neuron differentiation; and regulation of transcription, DNA-templated. Predicted to localize to nucleus. Is expressed in brain; notochord; pharyngeal arch; and retinal ganglion cell layer. Orthologous to human IRX6 (iroquois homeobox 6).
Genome Resources
Note
None
Expression
All Expression Data
11 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With irx6a Human Ortholog
No data available
Associated With irx6a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Domain IPR008422 Homeobox KN domain
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length Homeobox, conserved site Homeobox domain Homeobox KN domain Homeobox-like domain superfamily
UniProtKB:Q1LYH5 235
UniProtKB:Q503Z8 477
UniProtKB:Q6DH21 212
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations