Gene

irx6a

ID

ZDB-GENE-040712-5

Name

iroquois homeobox 6a

Symbol

irx6a Nomenclature History

Previous Names

ziro6a (1)
zgc:109993

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific; and sequence-specific DNA binding activity. Predicted to be involved in cell development; neuron differentiation; and regulation of transcription, DNA-templated. Predicted to localize to nucleus. Is expressed in brain; notochord; pharyngeal arch; and retinal ganglion cell layer. Orthologous to human IRX6 (iroquois homeobox 6).

Genome Resources

Note

None

Expression

All Expression Data

11 figures from 6 publications

Cross-Species Comparison

High Throughput Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With irx6a Human Ortholog

No data available

Associated With irx6a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017970	Homeobox, conserved site
Domain	IPR001356	Homeobox domain
Domain	IPR008422	Homeobox KN domain
Homologous_superfamily	IPR009057	Homeobox-like domain superfamily