ZFIN ID: ZDB-GENE-040712-4
Gene Name: iroquois homeobox 4b
Gene Symbol: irx4b    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: ziro4b (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to localize to the nucleus. Is expressed in ectoderm; nervous system; presumptive diencephalon; and presumptive rhombomere 1. Orthologous to human IRX4 (iroquois homeobox 4).
Genome Resources: Alliance (1),  Gene:474318 (1),  Ensembl(GRCz11):ENSDARG00000036051 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa73 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12344 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa23541 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH irx4b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH irx4b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of transcription, DNA-templated (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR001356 Homeobox domain
    Domain IPR003893 Iroquois-class homeodomain protein
    Domain IPR008422 Homeobox KN domain
    Homologous_superfamily IPR009057 Homeobox-like domain superfamily
    Conserved_site IPR017970 Homeobox, conserved site
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA irx4b-202 (1)    Ensembl 1818
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM irx4b No data available
    MARKER RELATIONSHIPS
    irx4b Contained in: [BAC] DKEY-261I16 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001020493 (1) 1740 bp
    Genomic GenBank:BX571830 143486 bp
    Select Tool
    Polypeptide UniProtKB:Q1LWG1 (1) 439 aa
    Sequence Information (all 13)
    ORTHOLOGY for irx4b ( Chr: 19 )
    CITATIONS (27)