ZFIN ID: ZDB-GENE-040630-7
Gene Name: POU class 1 homeobox 1
Gene Symbol: pou1f1
Sequence Ontology ID : SO:0000704

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Previous Names: pit-1 (1), Pit1 (1)

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(Including Attributions)
Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 22 figures from 16 publications
Directly Submitted Expression Data: 6 figures (7 images) from Thisse et al., 2005 [eu451]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Larval:Day 6 (144.0h-168.0h)
  adenohypophyseal placode, adenohypophysis, hypophysis, unspecified (all 5) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
pou1f1_unspecified Unspecified Unknown Unknown
sa8555 Point Mutation Unknown Premature Stop ENU
sa41392 Point Mutation Unknown Premature Stop ENU
t21379 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • t22072 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-pou1f1 (1)
    PHENOTYPE
    Data: 2 figures from Phenotype Annotation (1994-2006)
    Observed in: brain, hypophysis, whole organism
    DISEASE ASSOCIATED WITH pou1f1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    hypopituitarism Pituitary hormone deficiency, combined, 1 613038
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell fate specification (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000327 (1)
  • InterPro:IPR001356 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR010982 (1)
  • InterPro:IPR013847 (1)
  • InterPro:IPR015586 (1)
  • InterPro:IPR017970 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS00035 (1)
  • PROSITE:PS00465 (1)
  • PROSITE:PS50071 (1)
  • PROSITE:PS51179 (1)
  • Pfam:PF00046 (1)
  • Pfam:PF00157 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA pou1f1-001 (1) 1170
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM pou1f1 No data available
    MARKER RELATIONSHIPS
    pou1f1Contained in: [BAC] CH211-224M9 (1) (order this)
    pou1f1Encodes: [EST] eu451 (1)
    [cDNA] MGC:193810 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212851 (1) 1170bp
    Genomic GenBank:CR361551 (1) 177606bp
    Select Tool
    Polypeptide UniProtKB:Q6TGI4 (1) 350aa
    Sequence Clusters UniGene:89712 (1)
    Sequence Information (all 22)
    OTHER pou1f1 GENE PAGES
  • Alliance (1)
  • Gene:405777 (1)
  • VEGA:OTTDARG00000021185 (1)
  • Ensembl(GRCz10):ENSDARG00000058924 (1)
  • ORTHOLOGY for pou1f1 (Chr: 9)
    CITATIONS (47)