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ZIRC
ZFIN ID: ZDB-GENE-040625-25
Gene Name: eukaryotic translation initiation factor 2B, subunit 1 alpha
Gene Symbol: eif2b1
Sequence Ontology ID : SO:0000704

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Previous Name: zgc:86660

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have translation initiation factor activity; predicted to be involved in translational initiation; orthologous to human EIF2B1 (eukaryotic translation initiation factor 2B subunit alpha).
GENE EXPRESSION
Directly Submitted Expression Data: 3 figures (6 images) from Thisse et al., 2004 [IMAGE:6894278]
Wild-type Stages, Structures: Pharyngula:Prim-15 (30.0h-36.0h) to Hatching:Long-pec (48.0h-60.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa12357 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40609 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH eif2b1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    leukoencephalopathy with vanishing white matter Leukoencephalopathy with vanishing white matter 603896
    DISEASE ASSOCIATED WITH eif2b1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cellular metabolic process (more)
    Cellular Component cytoplasm (more)
    Molecular Function translation initiation factor activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000649 (1)
  • InterPro:IPR037171 (1)
  • Pfam:PF01008 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA eif2b1-201 (1) 1218
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM eif2b1 No data available
    MARKER RELATIONSHIPS
    eif2b1Contained in: [BAC] CH211-157P22 (1) (order this), DKEY-204G14 (1) (order this)
    eif2b1Encodes: [EST] IMAGE:6894278 (1) (order this)
    [cDNA] MGC:86660 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001002060 (1) 1176bp
    Genomic GenBank:CT978957 (1) 164556bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4ILD9 (1) 302aa
    Sequence Clusters UniGene:76300 (1)
    Sequence Information (all 16)
    ORTHOLOGY for eif2b1 (Chr: 5)
    CITATIONS (17)