Gene

lum

ID
ZDB-GENE-040625-24
Name
lumican
Symbol
lum Nomenclature History
Previous Names
  • lumican (1)
  • zgc:86661 (1)
  • zlum (1)
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Involved in collagen fibril organization and embryonic camera-type eye morphogenesis. Predicted to localize to extracellular space. Is expressed in several structures, including digestive system; epidermis; head mesenchyme; heart; and nervous system. Human ortholog(s) of this gene implicated in carotid artery disease; coronary artery disease; and pancreatic cancer. Orthologous to human LUM (lumican).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
11 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Yeh et al., 2010
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lum Human Ortholog
No data available
Associated With lum Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000372 Leucine-rich repeat N-terminal domain
Family IPR027219 Lumican
Homologous_superfamily IPR032675 Leucine-rich repeat domain superfamily
Repeat IPR001611 Leucine-rich repeat
Repeat IPR003591 Leucine-rich repeat, typical subtype
Domain Details Per Protein
Protein Length Leucine-rich repeat Leucine-rich repeat domain superfamily Leucine-rich repeat N-terminal domain Leucine-rich repeat, typical subtype Lumican
UniProtKB:Q6IQQ7 344
UniProtKB:F1R6G3 372
UniProtKB:A8BBA0 344
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-lum polyclonal Rabbit
  • IHC
  • WB
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations