ZFIN ID: ZDB-GENE-040625-120
Gene Name: guided entry of tail-anchored proteins factor 3, ATPase
Gene Symbol: get3    Nomenclature History

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Previous Names: asna1, trc40 (1), wu:fd05d03, zgc:56540, zgc:86799 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have ATPase activity. Involved in posttranslational protein targeting to endoplasmic reticulum membrane and synapse assembly. Predicted to localize to GET complex. Orthologous to human GET3 (guided entry of tail-anchored proteins factor 3, ATPase).
Genome Resources: Alliance (1),  Gene:325704 (1),  Ensembl(GRCz11):ENSDARG00000018190 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:56540]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la021297Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • re02 Small Deletion Unknown Unknown CRISPR
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-get3 1
    MO1-get3 N/A 1
    MO2-get3 N/A 1
    DISEASE ASSOCIATED WITH get3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH get3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process posttranslational protein targeting to endoplasmic reticulum membrane (more)
    Cellular Component cytoplasm (more)
    Molecular Function ATPase activity (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA asna1-201 (1)    Ensembl 4613
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM get3 No data available
    MARKER RELATIONSHIPS
    get3 Contained in: [BAC] DKEY-121B10 (1) (order this)
    get3 Contains: [SNP] rs3727549 (1)
    get3 Encodes: [EST] fd05d03 (1), fc64a01 (1), fc96b03 (1)
    [cDNA] MGC:56540 (1), MGC:86799 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001002298 (1) 1423 nt
    Genomic GenBank:BX901942 (1) 166521 nt
    Select Tool
    Polypeptide UniProtKB:Q6IQE5 (1) 341 aa
    Sequence Information (all 21)
    ORTHOLOGY for get3 ( Chr: 1 )
    CITATIONS (33)