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ZIRC
ZFIN ID: ZDB-GENE-040615-1
Gene Name: NK1 transcription factor related 2-like,a
Gene Symbol: nkx1.2la    Nomenclature History

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Previous Names: sax1 (1), zsax1 (1), zgc:101023

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Predicted to be involved in cell differentiation and positive regulation of transcription by RNA polymerase II. Predicted to localize to the nucleus. Is expressed in several structures, including axis; nervous system; neural tube; periderm; and tail bud. Orthologous to human NKX1-2 (NK1 homeobox 2).
Genome Resources: Alliance (1),  Gene:405755 (1),  Ensembl(GRCz11):ENSDARG00000006350 (1)
GENE EXPRESSION
All Expression Data: 8 figures from 3 publications
Directly Submitted Expression Data: 6 figures (16 images) from Thisse et al., 2004 [IMAGE:7150990]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa15517 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH nkx1.2la HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nkx1.2la VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of transcription, DNA-templated (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 8)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA nkx1.2la-201 (1)    Ensembl 3319
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nkx1.2la No data available
    MARKER RELATIONSHIPS
    nkx1.2la Contained in: [BAC] DKEYP-34H12 (1)
    nkx1.2la Encodes: [EST] IMAGE:7150990 (1) (order this)
    [cDNA] MGC:101023 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212830 (1) 914 bp
    Genomic GenBank:BX294129 (1) 156627 bp
    Select Tool
    Polypeptide UniProtKB:B8A4P8 (1) 270 aa
    Sequence Clusters UniGene:88551 (1)
    Sequence Information (all 14)
    ORTHOLOGY for nkx1.2la ( Chr: 13 )
    CITATIONS (26)