ZFIN ID: ZDB-GENE-040611-1
Gene Name: neuropilin 1b
Gene Symbol: nrp1b    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have growth factor binding activity; metal ion binding activity; and transmembrane signaling receptor activity. Involved in several processes, including axon guidance; regulation of vascular endothelial growth factor receptor signaling pathway; and vasculature development. Predicted to localize to integral component of membrane. Is expressed in cranial neural crest cell; mid cerebral vein; retinal ganglion cell layer; somite; and trunk vasculature. Orthologous to human NRP1 (neuropilin 1).
Genome Resources: Alliance (1),  Gene:402973 (1),  Ensembl(GRCz11):ENSDARG00000027290 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fh278 Point Mutation Unknown Premature Stop ENU
  • China Zebrafish Resource Center (CZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • fh279 Point Mutation Unknown Unknown ENU
    la028822Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • nrp1b_unrecovered Point Mutation Unknown Unknown ENU
    sa9247 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19852 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-nrp1b
    1
    CRISPR2-nrp1b
    1
    CRISPR3-nrp1b
    1
    CRISPR4-nrp1b
    1
    MO1-nrp1b N/A 2
    MO2-nrp1b N/A 2
    MO3-nrp1b N/A 2
    MO4-nrp1b N/A 1
    DISEASE ASSOCIATED WITH nrp1b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nrp1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process response to hypoxia (more)
    Cellular Component integral component of membrane (more)
    Molecular Function protein binding (more)
    GO Terms (all 22)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA nrp1b-202 (1)    Ensembl 1387
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nrp1b No data available
    MARKER RELATIONSHIPS
    nrp1b Contained in: [BAC] DKEY-218A22 (1) (order this)
    nrp1b Encodes: [cDNA] MGC:158182 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_205674 (1) 4633 nt
    Genomic GenBank:BX088727 (1) 185178 nt
    Select Tool
    Polypeptide UniProtKB:A3KNA2 (1) 959 aa
    Sequence Information (all 27)
    ORTHOLOGY for nrp1b ( Chr: 2 )
    CITATIONS (48)