Gene

nrp1b

ID
ZDB-GENE-040611-1
Name
neuropilin 1b
Symbol
nrp1b Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have several functions, including heparin binding activity; metal ion binding activity; and transmembrane signaling receptor activity. Involved in regulation of vascular endothelial growth factor receptor signaling pathway; response to hypoxia; and vasculature development. Predicted to localize to integral component of membrane. Is expressed in cranial neural crest cell; mid cerebral vein; retinal ganglion cell layer; somite; and trunk vasculature. Orthologous to human NRP1 (neuropilin 1).
Genome Resources
Note
None
Expression
All Expression Data
14 figures from 11 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nrp1b Human Ortholog
No data available
Associated With nrp1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000421 Coagulation factor 5/8 C-terminal domain
Domain IPR000859 CUB domain
Domain IPR000998 MAM domain
Domain IPR022579 Neuropilin, C-terminal
Family IPR014648 Neuropilin
Family IPR027146 Neuropilin-1
Homologous_superfamily IPR008979 Galactose-binding-like domain superfamily
Homologous_superfamily IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
Homologous_superfamily IPR035914 Spermadhesin, CUB domain superfamily
Domain Details Per Protein
Protein Length Coagulation factor 5/8 C-terminal domain Concanavalin A-like lectin/glucanase domain superfamily CUB domain Galactose-binding-like domain superfamily MAM domain Neuropilin Neuropilin-1 Neuropilin, C-terminal Spermadhesin, CUB domain superfamily
UniProtKB:Q6T869 871
UniProtKB:A2BEM4 327
UniProtKB:A0A0B5JK15 894
UniProtKB:Q6T870 959
UniProtKB:F1QHA9 540
UniProtKB:Q6RT22 959
UniProtKB:A3KNA2 959
UniProtKB:Q69DB7 959
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations