ZFIN ID: ZDB-GENE-040513-7
Gene Name: cadherin-related 23
Gene Symbol: cdh23
Previous Names: ush1d (1), cadherin 23 (1), spu, sputnik
Location: Chr: 13   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 5 figures from 4 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Adult (90d-730d, breeding adult)
  diencephalic nucleus, dorsal caudal thalamic nucleus, eminentia thalami brain nucleus, GABAergic neuron (all 10) expand
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 13 genotypes
Alleles: cdh23_unspecified, la012407Tg, nl9, ru609, t23576 (all 10) expand
Knockdown reagents: MO1-cdh23 (1)
PHENOTYPE
Data: 12 figures from 8 publications
Observed in: afferent neuron neuron projection, afferent neuron neuron projection development, afferent neuron, anterior macula stereocilium bundle (all 21) expand

Phenotype of Human Orthologue OMIM Phenotype ID
Deafness, autosomal recessive 12 601386
Usher syndrome, type 1D 601067
Usher syndrome, type 1D/F digenic 601067
GENE ONTOLOGY
Ontology GO Term
Biological Process antibiotic transport (more)
Cellular Component cilium (more)
Molecular Function antibiotic transporter activity (more)
GO Terms (all 18)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002126 (1)
  • InterPro:IPR015919 (1)
  • InterPro:IPR020894 (1)
  • PROSITE:PS00232 (1)
  • PROSITE:PS50268 (1)
  • Pfam:PF00028 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cdh23-001 (1) 1704
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cdh23 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    cdh23 Contained in: [BAC] CH211-180G15 (1) (order this), CH211-236A3 (1) (order this), DKEY-223L5 (1), DKEY-261I20 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_214809 (1) 11045 bp
    Genomic GenBank:BX510660 (1) 172425 bp
    Select Tool
    Polypeptide UniProtKB:Q6QQE1 (1) 3366 aa
    Sequence Clusters UniGene:92041 (1)
    Sequence Information (all 21)
    OTHER cdh23 GENE PAGES
  • Gene:407978 (1)
  • VEGA:OTTDARG00000029508 (1)
  • Ensembl(Zv9):ENSDARG00000094454 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish cdh23 13  
    Human CDH23 10 (10q22.1)
  • OMIM:605516
  • Gene:64072
  • Orthology Details
    CITATIONS (40)