ZFIN ID: ZDB-GENE-040513-7
Gene Name: cadherin-related 23
Gene Symbol: cdh23
Previous Names: cadherin 23 (1), spu, sputnik, ush1d (1)
Location: Chr: 13   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 6 figures from 5 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Adult (90d-730d, breeding adult)
  diencephalic nucleus, dorsal caudal thalamic nucleus, eminentia thalami brain nucleus, GABAergic neuron (all 11) expand
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 13 Genotypes
Knockdown reagents: MO1-cdh23 (1)

Allele Type Mutagen Suppliers
cdh23_unspecified Unspecified
la012407Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • nl9 Point Mutation ENU
    ru609 Unknown
    t23576 Point Mutation
  • European Zebrafish Resource Center (EZRC) (order this)
  • tc242b Point Mutation
  • Nüsslein-Volhard Lab
  • European Zebrafish Resource Center (EZRC) (order this)
  • tc317e Insertion
  • Nüsslein-Volhard Lab
  • European Zebrafish Resource Center (EZRC) (order this)
  • te370e Insertion ENU
  • Nüsslein-Volhard Lab
  • European Zebrafish Resource Center (EZRC) (order this)
  • tj264 Point Mutation
  • Nüsslein-Volhard Lab
  • European Zebrafish Resource Center (EZRC) (order this)
  • tz300 Point Mutation
  • European Zebrafish Resource Center (EZRC) (order this)
  • Nüsslein-Volhard Lab
  • PHENOTYPE
    Data: 12 figures from 8 publications
    Observed in: afferent neuron neuron projection, afferent neuron neuron projection development, afferent neuron, anterior macula stereocilium bundle (all 21) expand

    Phenotype of Human Orthologue OMIM Phenotype ID
    Deafness, autosomal recessive 12 601386
    Usher syndrome, type 1D 601067
    Usher syndrome, type 1D/F digenic 601067
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process auditory receptor cell development (more)
    Cellular Component cilium (more)
    Molecular Function antibiotic transporter activity (more)
    GO Terms (all 17)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002126 (1)
  • InterPro:IPR015919 (1)
  • InterPro:IPR020894 (1)
  • PROSITE:PS00232 (1)
  • PROSITE:PS50268 (1)
  • Pfam:PF00028 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cdh23-001 (1) 1704
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cdh23 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    cdh23 Contained in: [BAC] CH211-180G15 (1) (order this), CH211-236A3 (1) (order this), DKEY-223L5 (1) (order this), DKEY-261I20 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_214809 (1) 11045 bp
    Genomic GenBank:BX510660 (1) 172425 bp
    Select Tool
    Polypeptide UniProtKB:Q6QQE1 (1) 3366 aa
    Sequence Clusters UniGene:92041 (1)
    Sequence Information (all 21)
    OTHER cdh23 GENE PAGES
  • Gene:407978 (1)
  • VEGA:OTTDARG00000029508 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish cdh23 13  
    Human CDH23 10 (10q22.1)
  • OMIM:605516
  • Gene:64072
  • Orthology Details
    CITATIONS (40)