ZFIN ID: ZDB-GENE-040513-7
Gene Name: cadherin-related 23
Gene Symbol: cdh23
Previous Names: cadherin 23 (1), spu, sputnik, ush1d (1)
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 6 figures from 5 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Adult (90d-730d, breeding adult)
  diencephalic nucleus, dorsal caudal thalamic nucleus, GABAergic neuron, inner ear (all 11) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
cdh23_unspecified Unspecified Unknown Unknown
la012407Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • nl9 Point Mutation Acceptor Splice Site Unknown ENU
    ru609 Unknown Unknown Unknown
    sa31961 Point Mutation Unknown Unknown ENU
    sa35577 Point Mutation Unknown Unknown ENU
    sa35578 Point Mutation Unknown Unknown ENU
    sa42289 Point Mutation Unknown Unknown ENU
    t23576 Point Mutation Unknown Unknown
  • European Zebrafish Resource Center (EZRC) (order this)
  • tc242b Point Mutation Unknown Unknown
  • European Zebrafish Resource Center (EZRC) (order this)
  • tc317e Insertion Unknown Cryptic Acceptor Splice Site, Frameshift, Premature Stop
  • European Zebrafish Resource Center (EZRC) (order this)
  • te370e Insertion Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tj264 Point Mutation Unknown Unknown
  • European Zebrafish Resource Center (EZRC) (order this)
  • tz300 Point Mutation Unknown Unknown
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: CRISPR1-cdh23 (1), CRISPR2-cdh23 (2), CRISPR3-cdh23 (2), MO1-cdh23 (1)
    PHENOTYPE
    Data: 12 figures from 8 publications
    Observed in: afferent neuron neuron projection, afferent neuron neuron projection development, afferent neuron, anterior macula stereocilium bundle (all 21) expand
    DISEASE ASSOCIATED WITH cdh23 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    autosomal recessive nonsyndromic deafness Deafness, autosomal recessive 12 601386
    Usher syndrome Usher syndrome, type 1D 601067
    Usher syndrome, type 1D/F digenic 601067
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process auditory receptor cell development (more)
    Cellular Component cilium (more)
    Molecular Function antibiotic transporter activity (more)
    GO Terms (all 19)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002126 (1)
  • InterPro:IPR015919 (1)
  • InterPro:IPR020894 (1)
  • InterPro:IPR033030 (1)
  • PROSITE:PS00232 (1)
  • PROSITE:PS50268 (1)
  • Pfam:PF00028 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cdh23-001 (1) 1704
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM cdh23 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    cdh23Contained in: [BAC] CH211-180G15 (1) (order this), CH211-236A3 (1) (order this), DKEY-223L5 (1) (order this), DKEY-261I20 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_214809 (1) 11045bp
    Genomic GenBank:BX510660 (1) 172425bp
    Select Tool
    Polypeptide UniProtKB:Q6QQE1 (1) 3366aa
    Sequence Clusters UniGene:92041 (1)
    Sequence Information (all 21)
    OTHER cdh23 GENE PAGES
  • Gene:407978 (1)
  • VEGA:OTTDARG00000029508 (1)
  • ORTHOLOGY for cdh23 (Chr: 13)
    Species Symbol Chromosome Accession # Evidence
    Human CDH23 10
  • Gene:64072
  • OMIM:605516
  • HGNC:13733
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (47)