ZFIN ID: ZDB-GENE-040513-6
Gene Name: acid-sensing (proton-gated) ion channel family member 4b
Gene Symbol: asic4b    Nomenclature History

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Previous Names: accn4b, zASIC4.2 (1), zgc:111839

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Exhibits cation channel activity. Involved in response to steroid hormone. Localizes to integral component of plasma membrane. Is expressed in brain; eye; gill; ovary; and photoreceptor cell. Orthologous to human ASIC4 (acid sensing ion channel subunit family member 4).
Genome Resources: Alliance (1),  Gene:407667 (1),  Ensembl(GRCz11):ENSDARG00000004243 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa12799 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14893 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16524 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33831 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40654 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44632 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-asic4b N/A 1
    DISEASE ASSOCIATED WITH asic4b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH asic4b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process response to steroid hormone (more)
    Cellular Component integral component of plasma membrane (more)
    Molecular Function cation channel activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA asic4b-201 (1)    Ensembl 2316
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-asic4b polyclonal Rabbit IHC, WB 4
    Ab2-asic4b polyclonal Rat IHC, WB 1
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM asic4b No data available
    MARKER RELATIONSHIPS
    asic4b Contained in: [BAC] CH211-260I9 (1), DKEY-226N16 (1) (order this)
    asic4b Encodes: [cDNA] MGC:111839 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_214786 (1) 2296 nt
    Genomic GenBank:CR853290 (1) 196624 nt
    Select Tool
    Polypeptide UniProtKB:Q502T2 (1) 558 aa
    Sequence Information (all 13)
    ORTHOLOGY for asic4b ( Chr: 6 )
    CITATIONS (26)