ZFIN ID: ZDB-GENE-040513-4
Gene Name: acid-sensing (proton-gated) ion channel 2
Gene Symbol: asic2    Nomenclature History

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Previous Names: zASIC2 (1), accn1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have ligand-gated sodium channel activity. Involved in response to steroid hormone. Predicted to localize to integral component of membrane and plasma membrane. Is expressed in several structures, including brain; eye; gill; olfactory rosette; and ovary. Orthologous to human ASIC2 (acid sensing ion channel subunit 2).
Genome Resources: Alliance (1),  Gene:407669 (1),  Ensembl(GRCz11):ENSDARG00000006849 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1891 Point Mutation Unknown Premature Stop ENU
sa11288 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14878 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18762 Point Mutation Unknown Premature Stop ENU
    sa31347 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40123 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH asic2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH asic2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process response to steroid hormone (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ligand-gated sodium channel activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA asic2-202 (1)    Ensembl 3155
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-asic2 polyclonal Rabbit IHC, WB LifeSpan BioSciences, Inc.
    5
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM asic2 No data available
    MARKER RELATIONSHIPS
    asic2 Contained in: [BAC] CH73-302K7 (1), CH73-368I2 (1), CH211-15N4 (1), CH211-202A10 (1), CH211-261N20 (1), DKEY-7F16 (1) (order this), DKEYP-114A6 (1)
    asic2 Encodes: [cDNA] MGC:193635 (1), MGC:193662 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_214788 (1) 3160 nt
    Genomic GenBank:BX470087 (1) 218404 nt Blast at MegaBLAST
    Polypeptide UniProtKB:B3DFR3 (1) 533 aa
    Sequence Information (all 30)
    ORTHOLOGY for asic2 ( Chr: 3 )
    CITATIONS (28)