ZFIN ID: ZDB-GENE-040513-3
Gene Name: acid-sensing (proton-gated) ion channel 1c
Gene Symbol: asic1c    Nomenclature History

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Previous Names: zASIC1.3 (1), accn2c, hest1 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Exhibits ligand-gated sodium channel activity. Predicted to be involved in cellular response to pH and protein homotrimerization. Localizes to integral component of plasma membrane. Is expressed in gill. Orthologous to human ASIC1 (acid sensing ion channel subunit 1) and ASIC3 (acid sensing ion channel subunit 3).
Genome Resources: Alliance (1),  Gene:407670 (1),  Ensembl(GRCz11):ENSDARG00000098428 (1)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
PHENOTYPE No data available
DISEASE ASSOCIATED WITH asic1c HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH asic1c VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cellular response to pH (more)
Cellular Component integral component of plasma membrane (more)
Molecular Function ligand-gated sodium channel activity (more)
GO Terms (all 12)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA asic1c-201 (1)    Ensembl 748
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM asic1c No data available
MARKER RELATIONSHIPS
asic1c Contained in: [BAC] DKEY-220L13 (1) (order this), DKEYP-87A6 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_214789 (1) 1602 nt
Genomic GenBank:CU019563 (1) 194521 nt
Select Tool
Polypeptide UniProtKB:Q708S6 (1) 529 aa
Sequence Information (all 21)
ORTHOLOGY for asic1c ( Chr: 24 )
CITATIONS (20)