ZFIN ID: ZDB-GENE-040426-989
Gene Name: dynein, light chain, roadblock-type 1
Gene Symbol: dynlrb1    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: km23 (1), zgc:56335

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Exhibits dynein intermediate chain binding activity. Involved in transforming growth factor beta receptor signaling pathway. Localizes to dynein complex. Is expressed in ovarian follicle. Orthologous to human DYNLRB1 (dynein light chain roadblock-type 1).
Genome Resources: Alliance (1),  Gene:394163 (1), 
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:56335]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa21923 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-dynlrb1 N/A 1
    MO2-dynlrb1 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH dynlrb1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dynlrb1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process transforming growth factor beta receptor signaling pathway (more)
    Cellular Component dynein complex (more)
    Molecular Function dynein intermediate chain binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dynlrb1-201 (1)    Ensembl 692
    dynlrb1-202 (1)    Ensembl 684
    dynlrb1-203 (1)    Ensembl 781
    Browsers: NCBI
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-dynlrb1 Rabbit WB 1
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dynlrb1 No data available
    MARKER RELATIONSHIPS
    dynlrb1 Contained in: [BAC] DKEY-57N24 (1) (order this)
    dynlrb1 Encodes: [cDNA] MGC:56335 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_201188 (1) 668 nt
    Genomic GenBank:CU467888 (1) 168058 nt
    Select Tool
    Polypeptide UniProtKB:Q7ZUX8 (1) 96 aa
    Sequence Information (all 10)
    ORTHOLOGY for dynlrb1 ( Chr: 11 )
    CITATIONS (20)