Gene

h2ax

ID
ZDB-GENE-040426-987
Name
H2A.X variant histone
Symbol
h2ax Nomenclature History
Previous Names
  • H2A.X (1)
  • h2afx
  • zgc:56329
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have DNA binding activity. Involved in cellular response to DNA damage stimulus. Predicted to localize to centrosome and chromosome. Is expressed in several structures, including brain; oocyte; proliferative region; sensory system; and unfertilized egg. Orthologous to human H2AX (H2A.X variant histone).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
16 figures from 11 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With h2ax Human Ortholog
No data available
Associated With h2ax Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR032458 Histone H2A conserved site
Domain IPR007125 Histone H2A/H2B/H3
Domain IPR032454 Histone H2A, C-terminal domain
Family IPR002119 Histone H2A
Homologous_superfamily IPR009072 Histone-fold
Domain Details Per Protein
Protein Length Histone-fold Histone H2A Histone H2A conserved site Histone H2A, C-terminal domain Histone H2A/H2B/H3
UniProtKB:Q7ZUY3 142
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab2-h2afx polyclonal Rabbit
  • WB
Cell Signaling Technology, Inc.
5
Ab3-h2afx polyclonal Rabbit
  • IHC
  • WB
Signalway Antibody Co.
3
Ab1-h2afx polyclonal
  • IHC
  • WB
13
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations