Gene

pex12

ID
ZDB-GENE-040426-929
Name
peroxisomal biogenesis factor 12
Symbol
pex12 Nomenclature History
Previous Names
  • zgc:56182
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have ubiquitin-protein transferase activity. Predicted to be involved in protein import into peroxisome matrix and protein monoubiquitination. Predicted to localize to integral component of peroxisomal membrane and peroxisomal importomer complex. Human ortholog(s) of this gene implicated in peroxisomal biogenesis disorder and peroxisome biogenesis disorder 3A. Orthologous to human PEX12 (peroxisomal biogenesis factor 12).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pex12 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
infantile Refsum disease Alliance Peroxisome biogenesis disorder 3B 266510
peroxisome biogenesis disorder 3A Alliance Peroxisome biogenesis disorder 3A (Zellweger) 614859
Refsum disease Alliance Peroxisome biogenesis disorder 3B 266510
Associated With pex12 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR006845 Pex, N-terminal
Family IPR017375 Peroxisome assembly protein 12
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Domain Details Per Protein
Protein Length Peroxisome assembly protein 12 Pex, N-terminal Zinc finger, RING/FYVE/PHD-type
UniProtKB:B0R157 350
UniProtKB:Q7ZV73 303
UniProtKB:Q6TNS0 350
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations