ZFIN is now using GRCz12tu for Genomic Data
Gene
lpp
- ID
- ZDB-GENE-040426-918
- Name
- LIM domain containing preferred translocation partner in lipoma
- Symbol
- lpp Nomenclature History
- Previous Names
-
- fc26e09
- wu:fc26e09
- zgc:56152 (1)
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable metal ion binding activity. Acts upstream of or within dorsal convergence. Predicted to be active in focal adhesion and stress fiber. Is expressed in several structures, including axis; cardiovascular system; digestive system; tail bud; and unfertilized egg. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to human LPP (LIM domain containing preferred translocation partner in lipoma).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56152 (4 images)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Vervenne et al., 2008
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| acute myeloid leukemia | Alliance | Leukemia, acute myeloid | 601626 |
| Lipoma |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001781 | Zinc finger, LIM-type |
Domain Details Per Protein
| Protein | Additional Resources | Length | Zinc finger, LIM-type |
|---|---|---|---|
| UniProtKB:Q7ZU85 | InterPro | 556 | |
| UniProtKB:A0AB32TPX2 | InterPro | 571 | |
| UniProtKB:A0AB32TT89 | InterPro | 556 |
- Genome Browsers
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-lpp | monoclonal | Mouse |
|
BD Biosciences
|
1 |
Plasmids
No data available
- Genome Browsers