Gene

tpm1

ID
ZDB-GENE-040426-854
Name
tropomyosin 1 (alpha)
Symbol
tpm1 Nomenclature History
Previous Names
  • TPM1-1 (1)
  • zgc:171719
  • zgc:55951 (1)
  • zgc:77009
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1Y; familial hypertrophic cardiomyopathy; and hypertrophic cardiomyopathy 3. Is expressed in adaxial cell; heart; and musculature system. Orthologous to human TPM1 (tropomyosin 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
12 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tpm1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
dilated cardiomyopathy 1Y Alliance Cardiomyopathy, dilated, 1Y 611878
dilated cardiomyopathy 1Y Alliance Left ventricular noncompaction 9 611878
hypertrophic cardiomyopathy 3 Alliance Cardiomyopathy, hypertrophic, 3 115196
Associated With tpm1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR000533 Tropomyosin
Homologous_superfamily IPR014751 DNA repair protein XRCC4-like, C-terminal
Domain Details Per Protein
Transcripts
Genome Browsers
No data available
No data available
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-tpm1 polyclonal IgG Rabbit
  • WB
ABclonal
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations