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ZIRC
ZFIN ID: ZDB-GENE-040426-854
Gene Name: tropomyosin 1 (alpha)
Gene Symbol: tpm1
Sequence Ontology ID : SO:0000704

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Previous Names: TPM1-1 (1), zgc:171719, zgc:55951 (1), zgc:77009

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(Including Attributions)
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have actin filament binding activity. Predicted to be involved in actin filament organization. Predicted to localize to the actin filament. Human ortholog(s) of this gene implicated in  ...
GENE EXPRESSION
All Expression Data: 11 figures from 5 publications
Directly Submitted Expression Data: 7 figures (21 images) from Thisse et al., 2004 [MGC:55951]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la023313Tg Transgenic Insertion Unknown Unknown DNA
la028711Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44342 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tpm1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    dilated cardiomyopathy 1Y Cardiomyopathy, dilated, 1Y 611878
    Left ventricular noncompaction 9 611878
    hypertrophic cardiomyopathy 3 Cardiomyopathy, hypertrophic, 3 115196
    DISEASE ASSOCIATED WITH tpm1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process actin filament organization (more)
    Cellular Component actin filament (more)
    Molecular Function actin filament binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000533 (1)
  • PROSITE:PS00326 (1)
  • Pfam:PF00261 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tpm1 No data available
    MARKER RELATIONSHIPS
    tpm1Encodes: [cDNA] MGC:55951 (1) (order this), MGC:77009 (1) (order this), MGC:171719 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200934 (1) 1719bp
    Genomic GenBank:CABZ01046955 (1)
    Polypeptide UniProtKB:A0A1L6UW63 (1) 284aa
    Sequence Clusters UniGene:103889 (1)
    Sequence Information (all 64)
    OTHER tpm1 GENE PAGES
  • Alliance (1)
  • Gene:393908 (1)
  • Ensembl(GRCz11):ENSDARG00000087402 (2)
  • ORTHOLOGY for tpm1 (Chr: 13)
    CITATIONS (33)