Gene

tubg1

ID
ZDB-GENE-040426-836
Name
tubulin, gamma 1
Symbol
tubg1 Nomenclature History
Previous Names
  • tubgl (1)
  • zgc:55894
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic sister chromatid segregation. Predicted to localize to cytoplasm; microtubule cytoskeleton; and nucleus. Is expressed in blastomere; oocyte stage III; and oocyte stage V. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations 4; inclusion body myositis; and muscular disease. Orthologous to several human genes including TUBG1 (tubulin gamma 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
8 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tubg1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
complex cortical dysplasia with other brain malformations 4 Alliance Cortical dysplasia, complex, with other brain malformations 4 615412
Associated With tubg1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017975 Tubulin, conserved site
Domain IPR003008 Tubulin/FtsZ, GTPase domain
Domain IPR018316 Tubulin/FtsZ, 2-layer sandwich domain
Family IPR000217 Tubulin
Family IPR002454 Gamma tubulin
Homologous_superfamily IPR008280 Tubulin/FtsZ, C-terminal
Homologous_superfamily IPR023123 Tubulin, C-terminal
Homologous_superfamily IPR036525 Tubulin/FtsZ, GTPase domain superfamily
Homologous_superfamily IPR037103 Tubulin/FtsZ, C-terminal domain superfamily
Domain Details Per Protein
Protein Length Gamma tubulin Tubulin Tubulin, conserved site Tubulin, C-terminal Tubulin/FtsZ, 2-layer sandwich domain Tubulin/FtsZ, C-terminal Tubulin/FtsZ, C-terminal domain superfamily Tubulin/FtsZ, GTPase domain Tubulin/FtsZ, GTPase domain superfamily
UniProtKB:Q7ZVM5 451
UniProtKB:B0JZL0 264
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab3-tubg1 polyclonal IgG Rabbit
GeneTex
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations