Gene

panx1a

ID
ZDB-GENE-040426-766
Name
pannexin 1a
Symbol
panx1a Nomenclature History
Previous Names
  • panx1
  • zgc:55631
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Exhibits gap junction hemi-channel activity and voltage-gated channel activity. Predicted to be involved in cation transport and cell-cell signaling. Localizes to ruffle membrane. Is expressed in several structures, including heart; integument; liver; nervous system; and pleuroperitoneal region. Orthologous to human PANX1 (pannexin 1).
Genome Resources
Note
None
Expression
All Expression Data
9 figures from 6 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With panx1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Oocyte maturation defect 7 618550
Associated With panx1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR000990 Innexin
Family IPR039099 Pannexin
Domain Details Per Protein
Protein Length Innexin Pannexin
UniProtKB:F1R791 417
UniProtKB:Q7ZUN0 417
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-panx1a polyclonal IgG Rabbit
  • IHC
  • WB
3
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations