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General Information
ZIRC
ZFIN ID: ZDB-GENE-040426-750
Gene Name: cAMP responsive element binding protein 1a
Gene Symbol: creb1a    Nomenclature History

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Previous Names: creb1, zgc:55598 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have DNA binding activity and DNA-binding transcription factor activity. Involved in convergent extension involved in axis elongation; midbrain-hindbrain boundary development; and somitogenesis. Predicted to localize to the nucleus. Is expressed in nervous system; presumptive neural retina; and proliferative region. Orthologous to human CREB1 (cAMP responsive element binding protein 1).
Genome Resources: Alliance (1),  Gene:573207 (1),  Ensembl(GRCz11):ENSDARG00000053586 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa5939 Point Mutation Unknown Premature Stop ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH creb1a HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Histiocytoma, angiomatoid fibrous, somatic 612160
DISEASE ASSOCIATED WITH creb1a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process convergent extension involved in axis elongation (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 8)
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA creb1a-201 (1)    Ensembl 2023
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
SignaFish
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM creb1a
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
Tg(hsp70l:creb1a_S133A-mCherry) hsp70l creb1amCherry Danio rerio 1 1
MARKER RELATIONSHIPS
creb1a Contained in: [BAC] DKEYP-8H3 (1)
creb1a Encodes: [cDNA] MGC:55598 (1) (order this), MGC:191289 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_200909 (1) 1968 bp
Genomic GenBank:CR762462 (1) 186636 bp
Select Tool
Polypeptide UniProtKB:Q803K8 (1) 318 aa
Sequence Clusters UniGene:144106 (1)
Sequence Information (all 12)
ORTHOLOGY for creb1a ( Chr: 1 )
CITATIONS (32)