Gene

usp25

ID
ZDB-GENE-040426-2847
Name
ubiquitin specific peptidase 25
Symbol
usp25 Nomenclature History
Previous Names
  • wu:fi33c05
  • wu:fo67e06
  • wu:fp97a04
  • zgc:55791
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to enable cysteine-type deubiquitinase activity. Acts upstream of or within cranial skeletal system development and dorsal/ventral pattern formation. Predicted to be located in cytoplasm. Predicted to be active in cytosol and nucleus. Orthologous to human USP25 (ubiquitin specific peptidase 25).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With usp25 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
{Epilepsy, idiopathic generalized, susceptibility to, 19} 621064
Associated With usp25 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR003903 Ubiquitin interacting motif
Conserved_site IPR018200 Ubiquitin specific protease, conserved site
Conserved_site IPR054108 Ubiquitin carboxyl-terminal hydrolase 25/28, UIM
Domain IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase
Domain IPR054109 UBA-like domain
Family IPR050164 Ubiquitin carboxyl-terminal hydrolases
Homologous_superfamily IPR009060 UBA-like superfamily
Homologous_superfamily IPR038765 Papain-like cysteine peptidase superfamily
Domain Details Per Protein
Protein Additional Resources Length Papain-like cysteine peptidase superfamily Peptidase C19, ubiquitin carboxyl-terminal hydrolase UBA-like domain UBA-like superfamily Ubiquitin carboxyl-terminal hydrolase 25/28, UIM Ubiquitin carboxyl-terminal hydrolases Ubiquitin interacting motif Ubiquitin specific protease, conserved site
UniProtKB:Q7ZVQ4 InterPro 1072
UniProtKB:A0A8M9QGK5 InterPro 1108
UniProtKB:A0A8M2BGH6 InterPro 1073
UniProtKB:A0A8M3AX40 InterPro 1165
UniProtKB:A0A0R4IQS2 InterPro 1162
UniProtKB:A0A8M3B6G9 InterPro 1166
UniProtKB:A0A8M2BGE7 InterPro 1163
UniProtKB:A0A8M3B3I3 InterPro 1165
UniProtKB:A0A8M3BD95 InterPro 1076
UniProtKB:A0AB32TVR4 InterPro 1104
UniProtKB:A0AB32TWG6 InterPro 1071
UniProtKB:A0AB32TY16 InterPro 1072
UniProtKB:A0AB32TYE3 InterPro 1071
UniProtKB:A0AB32TZ10 InterPro 1075
UniProtKB:A0AB32U0N6 InterPro 1072
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA usp25-201 (1) Ensembl 4,049 nt
mRNA usp25-202 (1) Ensembl 7,474 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations