ZFIN Gene: usp25

ZFIN ID: ZDB-GENE-040426-2847

ZFIN ID: ZDB-GENE-040426-2847

Gene Name:

ubiquitin specific peptidase 25

Gene Symbol:

usp25

Sequence Ontology ID :

SO:0001217

Previous Names:

wu:fi33c05, wu:fo67e06, wu:fp97a04, zgc:55791

Location:

Chr: 10 Mapping Details/Browsers

Nomenclature History

AUTOMATED DESCRIPTION

Predicted to have cysteine-type endopeptidase activity and thiol-dependent ubiquitin-specific protease activity. Involved in cranial skeletal system development and dorsal/ventral pattern formation. ...

GENE EXPRESSION
Directly Submitted Expression Data:	1 figure (1 image) from Thisse et al., 2004 [MGC:55791]
Wild-type Stages, Structures:	Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
	unspecified
Curated Microarray Expression:	GEO (1)

MUTATIONS AND SEQUENCE TARGETING REAGENTS

Allele	Type	Localization	Consequence	Mutagen	Suppliers
la027185Tg	Transgenic Insertion	Unknown	Unknown	DNA	Zebrafish International Resource Center (ZIRC) (order this)
sa11988	Point Mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa16746	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa18443	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa21787	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa34963	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa41714	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)

Targeting reagents:

PHENOTYPE

Data:	2 figures from 2 publications
Observed in:	central nervous system ethmoid cartilage forebrain head mandibular arch skeleton pharyngeal arch cartilage post-vent region somite trunk whole organism

DISEASE ASSOCIATED WITH usp25 HUMAN ORTHOLOG No data available

DISEASE ASSOCIATED WITH usp25 VIA EXPERIMENTAL MODELS No data available

GENE ONTOLOGY

Ontology	GO Term
Biological Process	cranial skeletal system development (more)
Molecular Function	hydrolase activity (more)

GO Terms (all 10)

PROTEIN FAMILIES, DOMAINS AND SITES
InterPro:IPR001394 (1) InterPro:IPR003903 (1) InterPro:IPR009060 (1) InterPro:IPR018200 (1) InterPro:IPR028889 (1) InterPro:IPR038765 (1)	PROSITE:PS00972 (1) PROSITE:PS00973 (1) PROSITE:PS50235 (1) PROSITE:PS50330 (1)	Pfam:PF00443 (1)

TRANSCRIPTS
Type	Name	Length (bp)	Analysis
mRNA	usp25-201 (1)	4049	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

GENE PRODUCT DESCRIPTION

INTERACTIONS AND PATHWAYS

ANTIBODIES No data available

PLASMIDS No data available

CONSTRUCTS WITH SEQUENCES FROM usp25 No data available

MARKER RELATIONSHIPS

usp25 Contained in:	[BAC] CH73-178E10 (1) (order this), CH211-149B2 (1) (order this)
usp25 Encodes:	[EST] fi33c05, fo67e06, fp97a04 [cDNA] MGC:55791 (1) (order this)

SEQUENCE INFORMATION

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_001001886 (1)	4086 bp	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:FP016248 (1)	89903 bp	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:A0A0R4IQS2 (1)	1162 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast
Sequence Clusters	UniGene:67618 (1)

Sequence Information (all 35)

OTHER usp25 GENE PAGES

Alliance (1)

Gene:406790 (1)

VEGA:OTTDARG00000035091 (1)

Ensembl(GRCz11):ENSDARG00000012314 (2)

ORTHOLOGY for usp25 ( Chr: 10 )

CITATIONS (26)

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