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ZIRC
ZFIN ID: ZDB-GENE-040426-2761
Gene Name: APEX nuclease (multifunctional DNA repair enzyme) 1
Gene Symbol: apex1
Sequence Ontology ID : SO:0001217

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Previous Names: hm:zehn1532, wu:fc13d11, zap1 (1), zgc:66204

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(Including Attributions)
Location: Chr: 4 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have DNA-(apurinic or apyrimidinic site) endonuclease activity; double-stranded DNA 3'-5' exodeoxyribonuclease activity; and phosphodiesterase I activity. Involved in several processes,  ...
GENE EXPRESSION
All Expression Data: 11 figures from 7 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:66204]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la024675Tg Transgenic Insertion Unknown Unknown DNA
sa11621 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH apex1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH apex1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process heart contraction (more)
    Cellular Component cytoplasm (more)
    Molecular Function NOT   oxidoreductase activity (more)
    GO Terms (all 26)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA apex1-201 (1) 2119
    apex1-203 (1) 579
    apex1-204 (1) 754
    apex1-205 (1) 388
    apex1-206 (1) 682
    apex1-207 (1) 709
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM apex1 No data available
    MARKER RELATIONSHIPS
    apex1 Contained in: [BAC] CH211-214J24 (1) (order this)
    apex1 Encodes: [EST] fc13d11, zehn1532 (1)
    [cDNA] MGC:66204 (1) (order this), MGC:113976 (1) (order this), MGC:191415 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_213421 (1) 2104 bp
    Genomic GenBank:BX323558 (1) 160379 bp
    Select Tool
    Polypeptide UniProtKB:F1QTR9 (1) 341 aa
    Sequence Clusters UniGene:20170 (1)
    Sequence Information (all 45)
    ORTHOLOGY for apex1 ( Chr: 4 )
    CITATIONS (46)