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ZIRC
ZFIN ID: ZDB-GENE-040426-2759
Gene Name: mitogen-activated protein kinase kinase 1
Gene Symbol: map2k1
Sequence Ontology ID : SO:0001217

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Previous Names: mek1 (1), si:ch211-242m18.2, wu:fj56a12, wu:fj61b01 (1), zgc:56557

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(Including Attributions)
Location: Chr: 18 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have MAP kinase kinase activity and protein serine/threonine kinase activity. Predicted to be involved in activation of MAPK activity; signal transduction by protein phosphorylation; and  ...
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6511 Point Mutation Unknown Premature Stop ENU
sa43086 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH map2k1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    cardiofaciocutaneous syndrome 3 Cardiofaciocutaneous syndrome 3 615279
    DISEASE ASSOCIATED WITH map2k1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process phosphorylation (more)
    Cellular Component cytoplasm (more)
    Molecular Function ATP binding (more)
    GO Terms (all 13)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA map2k1-201 (1) 2093
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    MARKER RELATIONSHIPS
    map2k1 Contained in: [BAC] CH73-94F11 (1) (order this), CH211-242M18 (1) (order this)
    map2k1 Encodes: [EST] fj56a12, fj61b01
    [cDNA] MGC:56557 (1) (order this), MGC:113988 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_213419 (1) 2115 bp
    Genomic GenBank:CT863714 (1) 62423 bp
    Select Tool
    Polypeptide UniProtKB:Q1LUY7 (1) 400 aa
    Sequence Clusters UniGene:107100 (1)
    Sequence Information (all 24)
    ORTHOLOGY for map2k1 ( Chr: 18 )
    CITATIONS (30)