ZFIN ID: ZDB-GENE-040426-2759
Gene Name: mitogen-activated protein kinase kinase 1
Gene Symbol: map2k1
Previous Names: si:ch211-242m18.2, wu:fj56a12, wu:fj61b01 (1), zgc:56557
Location: Chr: 18 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: Fig. 4 from Nguyen et al., 2011
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH map2k1 HUMAN ORTHOLOG 
Disease Ontology Term OMIM Term OMIM Phenotype ID
cardiofaciocutaneous syndrome Cardiofaciocutaneous syndrome 3 615279
GENE ONTOLOGY 
Ontology GO Term
Biological Process phosphorylation (more)
Cellular Component cytoplasm (more)
Molecular Function ATP binding (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000719 (1)
  • InterPro:IPR002290 (1)
  • InterPro:IPR008271 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR017441 (1)
  • PROSITE:PS00107 (1)
  • PROSITE:PS00108 (1)
  • PROSITE:PS50011 (1)
  • Pfam:PF00069 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA map2k1-001 (1) 2093
    GENE PRODUCT DESCRIPTION No description available
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM map2k1
    Tg(hsp70l:map2k1,myl7:EGFP), Tg(hsp70l:map2k1_S219D_S223D,myl7:EGFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    map2k1Contained in: [BAC] CH73-94F11 (1) (order this), CH211-242M18 (1) (order this)
    map2k1Encodes: [EST] fj56a12, fj61b01
    [cDNA] MGC:56557 (1) (order this), MGC:113988 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_213419 (1) 2115bp
    Genomic GenBank:CT863714 (1) 62423bp
    Select Tool
    Polypeptide UniProtKB:Q1LUY7 (1) 400aa
    Sequence Clusters UniGene:107100 (1)
    Sequence Information (all 23)
    OTHER map2k1 GENE PAGES 
  • Gene:406728 (1)
  • VEGA:OTTDARG00000023382 (1)
  • Ensembl(GRCz10):ENSDARG00000007825 (1)
  • ORTHOLOGY for map2k1 (Chr: 18) 
    Species Symbol Chromosome Accession # Evidence
    Human MAP2K1 15
  • Gene:5604
  • OMIM:176872
  • HGNC:6840
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (23)