Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-040426-2759
Gene Name: mitogen-activated protein kinase kinase 1
Gene Symbol: map2k1
Previous Names: si:ch211-242m18.2, wu:fj56a12, wu:fj61b01 (1), zgc:56557
Location: Chr: 18   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: Fig. 4 from Nguyen et al., 2011
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS No data available
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Cardiofaciocutaneous syndrome 3 615279
GENE ONTOLOGY
Ontology GO Term
Biological Process phosphorylation (more)
Molecular Function ATP binding (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000719 (1)
  • InterPro:IPR002290 (1)
  • InterPro:IPR008271 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR017441 (1)
  • PROSITE:PS00107 (1)
  • PROSITE:PS00108 (1)
  • PROSITE:PS50011 (1)
  • Pfam:PF00069 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA map2k1-001 (1) 2093
    GENE PRODUCT DESCRIPTION No description available
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM map2k1
    Tg(hsp70l:map2k1,myl7:EGFP), Tg(hsp70l:map2k1_S219D_S223D,myl7:EGFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    map2k1 Contained in: [BAC] CH73-94F11 (1) (order this), CH211-242M18 (1) (order this)
    map2k1 Encodes: [EST] fj56a12, fj61b01
    [cDNA] MGC:56557 (1) (order this), MGC:113988 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_213419 (1) 2115 bp
    Genomic GenBank:CT863714 (1) 62423 bp
    Select Tool
    Polypeptide UniProtKB:Q1LUY7 (1) 400 aa
    Sequence Clusters UniGene:107100 (1)
    Sequence Information (all 23)
    OTHER map2k1 GENE PAGES
  • Gene:406728 (1)
  • VEGA:OTTDARG00000023382 (1)
  • Ensembl(Zv9):ENSDARG00000007825 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish map2k1 18  
    Human MAP2K1 15 (15q22.1-q22.33)
  • OMIM:176872
  • Gene:5604
  • Orthology Details
    CITATIONS (19)