ZFIN ID: ZDB-GENE-040426-2695
Gene Name: actin related protein 1, centractin
Gene Symbol: actr1    Nomenclature History

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Previous Names: hm:zehn1110, wu:fc22g09, wu:fc56d01, wu:fy52e08, zehn1110, zgc:56317 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to contribute to cytoskeletal protein-membrane anchor activity. Predicted to be involved in establishment of mitotic spindle orientation and nuclear migration along microtubule. Predicted to localize to cell cortex region; centrosome; and dynactin complex. Orthologous to several human genes including ACTR1B (actin related protein 1B).
Genome Resources: Alliance (1),  Gene:406681 (1),  Ensembl(GRCz11):ENSDARG00000011611 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:56317]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6183 Point Mutation Unknown Premature Stop ENU
sa31803 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-actr1 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH actr1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH actr1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component cytoplasm (more)
    Molecular Function ATP binding (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA actr1-201 (1)    Ensembl 2540
    actr1-202 (1)    Ensembl 1239
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM actr1 No data available
    MARKER RELATIONSHIPS
    actr1 Contained in: [BAC] CH211-180B9 (1)
    actr1 Encodes: [EST] fc22g09, fc56d01, fy52e08, zehn1110
    [cDNA] MGC:56317 (1), MGC:113996 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_213372 (1) 2544 nt
    Genomic GenBank:AL935178 (1) 144027 nt
    Select Tool
    Polypeptide UniProtKB:Q7ZUZ2 (1) 376 aa
    Sequence Information (all 18)
    ORTHOLOGY for actr1 ( Chr: 10 )
    CITATIONS (27)