Gene

dao.2

ID
ZDB-GENE-040426-2634
Name
D-amino-acid oxidase, tandem duplicate 2
Symbol
dao.2 Nomenclature History
Previous Names
  • zgc:76928
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have D-amino-acid oxidase activity. Predicted to be involved in D-alanine catabolic process; D-serine catabolic process; and proline catabolic process. Predicted to localize to cytoplasm. Is expressed in several structures, including blastomere; central nervous system; extension; pleuroperitoneal region; and somite. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human DAO (D-amino acid oxidase).
Genome Resources
Note
None
Expression
All Expression Data
from Chen et al., 2007
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dao.2 Human Ortholog
No data available
Associated With dao.2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR006181 D-amino acid oxidase, conserved site
Domain IPR006076 FAD dependent oxidoreductase
Family IPR023209 D-amino-acid oxidase
Domain Details Per Protein
Protein Length D-amino-acid oxidase D-amino acid oxidase, conserved site FAD dependent oxidoreductase
UniProtKB:Q6NY97 348
UniProtKB:A2BGT2 348
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Orthology Note
This gene, dao.1(ZDB-GENE-050913-127) and dao.3 (ZDB-GENE-040426-1894) are located next to each other in the genome and appear to be the result of a tandem duplication. The tandem duplicates appear to be the orthologs of human DAO and mouse Dao based on amino acid identity and conserved location.
Citations