ZFIN Gene: dao.2

ZFIN ID: ZDB-GENE-040426-2634

ZFIN ID: ZDB-GENE-040426-2634

Gene Name:

D-amino-acid oxidase, tandem duplicate 2

Gene Symbol:

dao.2 Nomenclature History

Previous Name:

zgc:76928

Gene Type:

protein_coding_gene

Location:

Chr: 5 Mapping Details/Browsers

Description:

Predicted to have D-amino-acid oxidase activity and FAD binding activity. Predicted to be involved in D-alanine catabolic process; D-serine catabolic process; and proline catabolic process. Is expressed in several structures, including blastomere; central nervous system; extension; pleuroperitoneal region; and somite. Orthologous to human DAO (D-amino acid oxidase).

Genome Resources:

Alliance (1), Gene:405800 (1), Ensembl(GRCz11):ENSDARG00000035603 (2)

GENE EXPRESSION
All Expression Data:	Fig. 2 from Chen et al., 2007
Wild-type Stages, Structures:	Zygote:1-cell (0.0h-0.75h) to Larval:Days 7-13 (168.0h-14d, 4.5mm, 8 teeth)
	blastomere brain extension floor plate rhombomere region floor plate spinal cord region forebrain gut head midbrain midbrain hindbrain boundary optic tectum otic vesicle pronephric duct somite 1 somite 2 somite 3 swim bladder ventrolateral optic tract yolk syncytial layer

MUTATIONS AND SEQUENCE TARGETING REAGENTS

Allele	Type	Localization	Consequence	Mutagen	Suppliers
sa20378	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa40392	Point Mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)

PHENOTYPE No data available

DISEASE ASSOCIATED WITH dao.2 HUMAN ORTHOLOG No data available

DISEASE ASSOCIATED WITH dao.2 VIA EXPERIMENTAL MODELS No data available

GENE ONTOLOGY

Ontology	GO Term
Biological Process	D-amino acid metabolic process (more)
Molecular Function	D-amino-acid oxidase activity (more)

GO Terms (all 9)

PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available

TRANSCRIPTS
Type	Name	Length (nt)	Analysis
mRNA	dao.2-201 (1)	1295	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Browsers: UCSC, NCBI, Ensembl, ZFIN

INTERACTIONS AND PATHWAYS

ANTIBODIES No data available

PLASMIDS No data available

CONSTRUCTS WITH SEQUENCES FROM dao.2 No data available

MARKER RELATIONSHIPS

dao.2 Contained in:	[BAC] DKEY-72N1 (1) (order this)
dao.2 Encodes:	[cDNA] MGC:76928 (1)

SEQUENCE INFORMATION

Type	Accession #	Length (nt/aa)	Analysis
RNA	RefSeq:NM_214732 (1)	1557 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX511005 (1)	139111 nt	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:A2BGT2 (1)	348 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

Sequence Information (all 10)

ORTHOLOGY for dao.2 ( Chr: 5 )

CITATIONS (18)

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