Gene
dao.2
- ID
- ZDB-GENE-040426-2634
- Name
- D-amino-acid oxidase, tandem duplicate 2
- Symbol
- dao.2 Nomenclature History
- Previous Names
-
- zgc:76928
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable D-amino-acid oxidase activity. Predicted to be involved in D-alanine catabolic process; D-serine catabolic process; and L-proline catabolic process. Predicted to act upstream of or within D-amino acid metabolic process. Predicted to be located in several cellular components, including cytosol; peroxisomal matrix; and presynaptic active zone. Predicted to be active in cytoplasm. Is expressed in several structures, including blastomere; central nervous system; extension; pleuroperitoneal region; and somite. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human DAO (D-amino acid oxidase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Chen et al., 2007
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | D-amino-acid oxidase | D-amino acid oxidase, conserved site | FAD dependent oxidoreductase |
|---|---|---|---|---|---|
| UniProtKB:Q6NY97 | InterPro | 348 |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance
- Gene Tree
- Ensembl
- Note
- This gene, dao.1(ZDB-GENE-050913-127) and dao.3 (ZDB-GENE-040426-1894) are located next to each other in the genome and appear to be the result of a tandem duplication. The tandem duplicates appear to be the orthologs of human DAO and mouse Dao based on amino acid identity and conserved location.