ZFIN ID: ZDB-GENE-040426-2487
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Gene Name: protein phosphatase 2, catalytic subunit, beta isozyme
Gene Symbol: ppp2cb    Nomenclature History

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Previous Names: fb17h07, fc05c02, fk24a01, wu:fb17h07, wu:fc05c02, wu:fk24a01, zgc:55808 (1), zgc:77172

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to have phosphoprotein phosphatase activity. Orthologous to human PPP2CB (protein phosphatase 2 catalytic subunit beta).
Genome Resources: Alliance (1),  Gene:406582 (1),  Ensembl(GRCz11):ENSDARG00000099241 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55808]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la017620Tg Transgenic Insertion Unknown Unknown DNA
sa21647 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-ppp2cb
    		1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ppp2cb HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ppp2cb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component cellular_component (more)
    Molecular Function hydrolase activity (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR004843 Calcineurin-like phosphoesterase domain, ApaH type
    Domain IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
    Homologous_superfamily IPR029052 Metallo-dependent phosphatase-like
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ppp2cb-201 (1)    Ensembl 738
    Select Tool
    ppp2cb-202 (1)    Ensembl 2020
    Select Tool
    Browsers: UCSC,  NCBI,  Ensembl,  ZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ppp2cb No data available
    MARKER RELATIONSHIPS
    ppp2cb Contained in: [BAC] DKEYP-73E12
    ppp2cb Encodes: [EST] fb17h07, fc05c02, fk24a01
    [cDNA] MGC:55808, MGC:77172 (1), MGC:174131 (1)
    ppp2cb Has Artifact: [EST] fb64b06
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_213293 (1) 1739 nt
    Select Tool
    Genomic GenBank:BX537303 (1) 204522 nt Blast at MegaBLAST
    Polypeptide UniProtKB:Q803G3 (1) 309 aa
    Select Tool
    Sequence Information (all 21)
    ORTHOLOGY for ppp2cb ( Chr: 10 )
    CITATIONS (27)