ZFIN is now using GRCz12tu for Genomic Data
        
        
        Gene
leo1
- ID
 - ZDB-GENE-040426-2435
 - Name
 - LEO1 homolog, Paf1/RNA polymerase II complex component
 - Symbol
 - leo1 Nomenclature History
 - Previous Names
 - 
    
        
    
    
        
        
- zgc:77374
 
 - Type
 - protein_coding_gene
 - Location
 - Chr: 18 Mapping Details/Browsers
 - Genome Assembly
 - GRCz12tu
 - Annotation Status
 - Current
 - Description
 - Predicted to enable RNA polymerase II C-terminal domain phosphoserine binding activity. Acts upstream of or within several processes, including embryonic cranial skeleton morphogenesis; glial cell differentiation; and xanthophore differentiation. Located in nucleus. Part of Cdc73/Paf1 complex. Is expressed in brain; eye; immature eye; pharyngeal arch; and somite. Orthologous to human LEO1 (LEO1 homolog, Paf1/RNA polymerase II complex component).
 - Genome Resources
 - Note
 - None
 - Comparative Information
 - 
    
        
        
            
        
    
    
    
 
- All Expression Data
 - 3 figures from 2 publications
 - Cross-Species Comparison
 - High Throughput Data
 - Thisse Expression Data
 - 
    
        
    
    
        
        
- MGC:77374 (1 image)
 
 
                
                    
                        Wild Type Expression Summary
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    - All Phenotype Data
 - 10 figures from 3 publications
 - Cross-Species Comparison
 - Alliance
 
                
                    
                        Phenotype Summary
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Mutations
                    
                    
                
                
            
        
        
    
        
            
            
    
    
                
                    
                        Human Disease
                    
                    
                
                
            
        
        
    
        
            
            
    
    
                
                    
                        Domain, Family, and Site Summary
                    
                    
                
                
            
        
        
    
        
            
                
    
        
    | Type | InterPro ID | Name | 
|---|---|---|
| Family | IPR007149 | Leo1-like protein | 
                
                    
                        Domain Details Per Protein
                    
                    
                
                
            
        
        
    
        
            
                
    
        
    | Protein | Additional Resources | Length | Leo1-like protein | 
|---|---|---|---|
| UniProtKB:Q6NYV9 | InterPro | 696 | 
- Genome Browsers
 
                
                    
                        Interactions and Pathways
                    
                    
                
                
            
        
        
    
        
            
            
    
    
        
    
No data available
    
        
        
    
    
    
                
                    
                        Plasmids
                    
                    
                
                
            
        
        
    
        
            
            
    
    
        
    
No data available
    
        
        
    
    
    - Genome Browsers