ZFIN ID: ZDB-GENE-040426-2435
Gene Name: LEO1 homolog, Paf1/RNA polymerase II complex component
Gene Symbol: leo1
Sequence Ontology ID : SO:0000704

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Previous Name: zgc:77374

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(Including Attributions)
Location: Chr: 18 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have RNA polymerase II C-terminal domain phosphoserine binding activity; involved in several processes, including animal organ development, melanocyte differentiation, and nervous system  ...
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:77374]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
knu6 Point Mutation Unknown Premature Stop ENU
la1186 Point Mutation Unknown Premature Stop ENU
sa2979 Point Mutation Unknown Premature Stop ENU
sa29073 Point Mutation Unknown Premature Stop ENU
sa43155 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44895 Point Mutation Unknown Unknown ENU
    Targeting reagents:
    PHENOTYPE
    Data: 9 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH leo1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH leo1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process embryonic cranial skeleton morphogenesis (more)
    Cellular Component Cdc73/Paf1 complex (more)
    Molecular Function RNA polymerase II C-terminal domain phosphoserine binding (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR007149 (1)
  • Pfam:PF04004 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA leo1-201 (1) 2284
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM leo1 No data available
    MARKER RELATIONSHIPS
    leo1Contained in: [BAC] DKEY-7C4 (1) (order this), DKEY-14B24 (1) (order this)
    leo1Encodes: [cDNA] MGC:77374 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_207067 (1) 2323bp
    Genomic GenBank:CR848839 (1) 101830bp
    Select Tool
    Polypeptide UniProtKB:Q6NYV9 (1) 696aa
    Sequence Clusters UniGene:79820 (1)
    Sequence Information (all 12)
    OTHER leo1 GENE PAGES
  • Alliance (1)
  • Gene:404599 (1)
  • VEGA:OTTDARG00000015029 (1)
  • Ensembl(GRCz11):ENSDARG00000055357 (2)
  • ORTHOLOGY for leo1 (Chr: 18)
    CITATIONS (28)