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ZIRC
ZFIN ID: ZDB-GENE-040426-2342
Gene Name: sprouty related EVH1 domain containing 2b
Gene Symbol: spred2b    Nomenclature History

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Previous Names: spred2, fb93f08, wu:fb93f08, zgc:77284

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to have protein kinase binding activity. Predicted to be involved in positive regulation of DNA damage response, signal transduction by p53 class mediator and regulation of protein modification process. Predicted to localize to the plasma membrane and transport vesicle membrane. Is expressed in brain and spinal cord. Orthologous to human SPRED2 (sprouty related EVH1 domain containing 2).
Genome Resources: Alliance (1),  Gene:793290 (1),  Ensembl(GRCz11):ENSDARG00000008372 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa35410 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH spred2b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH spred2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process multicellular organism development (more)
    Cellular Component cytoplasm (more)
    Molecular Function protein kinase binding (more)
    GO Terms (all 12)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA spred2b-201 (1)    Ensembl 3030
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM spred2b No data available
    MARKER RELATIONSHIPS
    spred2b Contained in: [BAC] DKEY-66M17 (1) (order this)
    spred2b Encodes: [EST] fb93f08
    [cDNA] MGC:77284 (1) (order this), MGC:198113 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_213234 (1) 3039 bp
    Genomic GenBank:BX629343 (1) 207677 bp Blast at MegaBLAST
    Polypeptide UniProtKB:A5PMN3 (1) 413 aa
    Sequence Clusters UniGene:33129 (1)
    Sequence Information (all 19)
    ORTHOLOGY for spred2b ( Chr: 13 )
    CITATIONS (21)